摘要
中药制剂是由多种中药配伍组成的,是一个复杂的分子体系,其分析鉴定工作存在较大难度。高效液相色谱与高分辨质谱联用系统(HPLC-HRMS)在中药复方的定性研究中发挥着重要作用。本论文通过探索将高分辨液相色谱质谱联用系统应用到中药学本科生实验教学实践中,建立了对中药制剂参松养心胶囊中5种特征性成分进行鉴定的实验教学方法。使学生了解高分辨质谱在中药制剂分析和鉴定中的重要应用,开阔了本校中药学专业本科生的科研视野,提高了学生对仪器分析的理解,对培养高素质高水平的药学本科生起到了积极作用。
The chemistry composition of traditional Chinese medicine(TCM)preparations which are composed of various TCM is complex.It is difficult to analysis or identification complex TCM ingredients.The qualitative research of TCM is greatly enhanced by the use of high performance liquid chromatography and high resolution mass spectrometry(HPLC-HRMS).This paper explores the application of a high-resolution liquid chromatography-mass spectrometry system in the experimental teaching practice of undergraduate Chinese medicine students,and establishes an experimental teaching method for identifying five characteristic components in the TCM preparation Shensong Yangxin Capsules.By utilizing high-resolution mass spectrometry,students can gain a deeper understanding of the key role of such technology in the analysis and identification of TCM preparations.This could expand the scientific research perspective of TCM undergraduates at our institution,enhance their comprehension of instrumental analysis,and contribute to cultivate high-quality and high-level pharmaceutical undergraduate students.
作者
李雯
王林
李焕勇
何乔
Li Wen;Wang Lin;Li Huanyong;He Qiao(Jinan University,Guangzhou 510632,China)
出处
《广东化工》
CAS
2024年第18期195-197,224,共4页
Guangdong Chemical Industry
基金
中国博士后基金项目(2021M701645)。
关键词
高分辨质谱
实验教学
仪器分析
中药制剂分析
成分鉴定
high resolution mass spectrometry
experimental teaching
instrumental analysis
analysis of traditional Chinese medicine preparations
composition identification
