乙型流感病毒感染后继发支气管肺曲霉病1例

A case of bronchopulmonary aspergillosis secondary to influenza B virus infection

报道1例乙型流感病毒感染后继发支气管肺曲霉病的诊疗情况。患者,女,33岁,临床表现为咳嗽、咳痰10余天,加重伴喘憋3 d,入院后患者迅速出现窒息,及时插管并清理呼吸道坏死及黏痰。支气管肺泡灌洗液GM试验阳性,呼吸道病原微生物检测结果示烟曲霉合并乙型流感病毒感染,采用伏立康唑、两性霉素B抗真菌治疗,奥司他韦抗病毒治疗,逐渐好转。

We report a case of bronchopulmonary aspergillosis secondary to influenza B virus infection.The patient,female,33 years old,clinically presented with cough and sputum for more than 10 days,aggravated with wheezing for 3 days.The patient was admitted to the hospital with rapid onset of asphyxia,and was promptly intubated and cleared of respiratory necrosis and mucous sputum.Bronchoalveolar lavage fluid GM test was positive,detection of respiratory pathogenic microorganisms showed Aspergillus fumigatus combined with influenza B virus infection,voriconazole,amphotericin B antifungal treatment,oseltamivir antiviral treatment,gradually improved.