痛风舒汤联合虎力散外敷治疗急性痛风性关节炎的临床观察

Clinical Observation of Tongfengshu Decoction Combined with External Application of Huli Powder in the Treatment of Acute Gouty Arthritiis

目的通过观察痛风舒汤联合虎力散对急性痛风性关节炎(湿热蕴结型)患者关节肿痛以及实验室指标的影响,探讨痛风舒汤联合虎力散对急性痛风性关节炎的疗效。方法选取急性痛风性关节炎患者90例,按随机数字表法分为对照组1、对照组2及观察组,每组30例。对照组1给予基础治疗,对照组2给予基础治疗+痛风舒汤口服,观察组给予基础治疗+痛风舒汤口服+虎力散外敷。收集治疗前及治疗1周后的关节肿痛程度、血尿酸水平、红细胞沉降率、白细胞计数和C反应蛋白水平的数据,评价3组患者的临床疗效。结果观察组止痛消肿疗效优于两个对照组(P<0.05)。在实验室指标方面,观察组降血尿酸、红细胞沉降率、白细胞计数和C反应蛋白水平明显优于对照组1(P<0.05),但和对照组2无明显差异(P>0.05)。结论痛风舒汤联合虎力散可以明显改善急性痛风性关节炎(湿热蕴结型)患者关节肿胀和疼痛,缓解临床症状,并具有一定的降血尿酸水平以及抗炎作用。

Objective:To observe the effect of Tongfengshu Decoction combined with Huli Powder on joint swelling and pain and laboratory indexes in patients with acute gouty arthritis(syndrome of accumulated dampnessheat),and to explore the curative effect of Tongfengshu Decoction combined with Huli Powder on acute gouty arthritis.Methods:A total of 90 patients with acute gouty arthritis were selected.According to the random number table method,they were divided into control group 1,control group 2 and observation group,with 30 cases in each group.The control group 1 was given basic treatment,the control group 2 was given basic treatment+Tongfengshu Decoction orally and the observation group was given basic treatment+Tongfengshu Decoction orally+Huli Powder for external application.Data on the degree of joint swelling and pain,serum uric acid levels,erythrocyte sedimentation rate,white blood cell counts,and C-reactive protein levels were collected before and 1 week after treatment,the data were analyzed to evaluate the clinical efficacy of Tongfengshu Decoction combined with external application of Huli Powder in the treatment of acute gouty arthritis.Results:The effect of reducing swelling and pain in the observation group was better than that in the two control groups(P<0.05).In terms of laboratory indexes,the levels of uric acid,erythrocyte sedimentation rate,white blood cell count and C-reactive protein in the observation group were significantly better than those in the control group 1(P<0.05),but there was no significant difference between the observation group and the control group 2(P>0.05).Conclusion:Tongfengshu Decoction combined with Huli Powder can significantly improve joint swelling and pain in patients with acute gouty arthritis(syndrome of accumulated dampness-heat),relieve clinical symptoms,reduce serum uric acid level and anti-inflammatory effect.