基于“宗气”理论探讨慢性阻塞性肺疾病发展为慢性肺源性心脏病的病因病机

Exploring the Etiology and Pathogenesis of Chronic Obstructive Pulmonary Disease Developing Into Chronic Pulmonary Heart Disease Based on The Theory of"Zong Qi"

慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)是一种临床上常见的呼吸系统疾病,可以合并发展为其他的慢性疾病;其中,慢性肺源性心脏病就多由COPD进一步发展而来,是一种涉及呼吸、循环等多系统的全身性疾病,可对患者生活质量产生重大消极影响。中医学理论认为COPD在发展成慢性肺源性心脏病的过程当中可导致肺、脾、肾、心等多个脏腑虚损,而“宗气”作为中医学理论当中人体之气的重要组成部分,其生成和生理功能的发挥与肺、脾、肾、心等多个脏器紧密关联,同时还可调控机体多个生理病理过程,进而可影响多类疾病的发生发展。文章通过检索国内外相关文献,并以中医学中的“宗气”理论为切入点,结合历代医家对于“宗气”的不同认识与现代医学研究,通过论述COPD发展为慢性肺源性心脏病的中西医研究进展以及“宗气”来源、生理功能和所处的位置等多个方面来探究COPD发展为慢性肺源性心脏病的病因病机,以期为进一步完善“宗气”理论指导下的COPD及慢性肺源性心脏病的相关诊治提供理论依据。

Chronic obstructive pulmonary disease is a common respiratory disease,which can be combined with other chronic diseases.Among them,chronic pulmonary heart disease is further developed from chronic obstructive pulmonary disease,which is a systemic disease involving respiration,circulation and other systems,which can have a significant negative impact on the quality of life of patients.Traditional Chinese medicine(TCM)theory holds that chronic obstructive pulmonary disease in the process of developing into chronic pulmonary heart disease can lead to the deficiency and damage of multiple viscera such as lung,spleen,kidney and heart.Zongqi,as an important part of human qi in TCM theory,is closely related to the formation and physiological function of organs such as lung,spleen,kidney and heart.At the same time,it can also regulate multiple physiological and pathological processes of the body,and then affect the occurrence and development of many kinds of diseases.In view of this,by searching relevant literature at home and abroad,and taking the theory of"Zong Qi"in traditional Chinese medicine as the starting point,the author combined the different understandings of"Zong Qi"of doctors in the past dynasties and modern medical research.The etiology and pathogenesis of the development of chronic obstructive pulmonary disease into chronic pulmonary heart disease are explored by discussing the research progress of traditional Chinese and Western medicine,the source of"Zongqi",physiological function and location of chronic obstructive pulmonary disease.In order to provide theoretical basis for further improving the diagnosis and treatment of chronic obstructive pulmonary disease and chronic pulmonary heart disease under the guidance of"Zongqi"theory.