孕妇维生素D缺乏与婴儿湿疹的关系

Association of maternal vitamin D deficiency and infantile eczema

维生素D(VD)是与人体骨骼健康和钙磷代谢密切相关的脂溶性维生素。人体VD缺乏已经成为全球性公共卫生问题,尤其是孕妇VD缺乏,不仅影响母体健康,还影响胎儿的生长发育和婴儿对未来多种疾病的易感性。近年来研究显示,充足的脐带血VD水平与1岁以下婴儿湿疹发病率降低相关。随着婴儿湿疹发病率的逐年升高,VD营养状况与湿疹的关系受到关注。目前,孕妇VD水平与婴儿湿疹关系的流行病学研究较少,且结果不一致。本文总结和分析了孕妇VD水平与婴儿湿疹的关系,为进一步探寻VD营养状况在婴儿湿疹发病中的作用、采取针对性防治措施提供理论依据。

Vitamin D(VD)is a fat-soluble vitamin closely related to bone health and calcium and phosphorus metabolism.VD deficiency in humans has become a global public health problem,especially in pregnant women as it affects maternal health and fetal growth,development,and susceptibility to many diseases.Recent studies have shown that adequate cord blood VD levels are associated with a reduced incidence of eczema in infants aged<1 year.With the increasing annual incidence of eczema in infants,its association with VD nutritional status has begun to receive attention.However,few epidemiological studies have investigated the association between VD levels during pregnancy and infantile eczema,and the results have been inconsistent.Therefore,this study reviews the association between VD nutritional status during pregnancy and infantile eczema,which may provide a theoretical basis for further exploring the role of VD nutritional status in the development of infantile eczema and taking targeted preventive and curative measures.