自体淋巴结移植治疗淋巴水肿研究进展

Advancesinthe autologous lymph node transplantation for the treatment of lymphedema

淋巴水肿是一种慢性、进行性、需要终身治疗的致残性疾病,可发生在身体的任何部位,四肢最为常见,临床表现为患肢的慢性肿胀、局部疼痛、皮肤萎缩和易感染。非增强磁共振淋巴管造影作为一种客观、可重复的影像学检查方法,可用于淋巴水肿的诊断和鉴别诊断、指导治疗以及疗效评价。过去十年,自体淋巴结移植取得了显著进展,成为治疗淋巴水肿的可行选择。本文综述淋巴水肿和自体淋巴结移植领域的最新进展,包括淋巴水肿的诊断、自体淋巴结移植手术的发展历史、适应证、供区和受区的选择、手术注意事项和术后常见并发症等。

Lymphedema is a chronic,progressive,and disabling condition that requires lifelong treatment and can occur anywhere in the body,most commonly in the extremities,with clinical manifestations of chronic swelling,local pain,skin atrophy,and susceptibility to infection of the affected limb.As an objective and repeatable imaging examination method,unenhanced magnetic resonance lymphangiography can be used for the diagnosis and differential diagnosis of lymphedema,guiding treatment and efficacy evaluation.Great progress has been achieved in of lymph node transplantation over the past 10 years.Currently,lymph node transplantation is no longer considered an experimental procedure and has become a selective therapy in patients with lymphedema.This article summarizes recent advances in lymphedema and lymph node transplantation,including lymphedema,surgical indications,donor sites and recipient sites,surgical precautions and common postoperative complications.