治疗性放射性核素的应用及展望

Application and Prospect of Therapeutic Radionuclides

放射性核素靶向治疗是一种有效的肿瘤治疗方法,它通过载体或介入技术将药物精准地传递至病灶,并发射出特定的射线能量,以最大限度地减少对健康细胞的破坏,从而实现治疗目标。治疗性放射性核素的类型、放射能量、物理半衰期、制备方法、毒性等因素决定了其在临床上的应用范围。该文综述治疗性放射性核素的特点和临床应用现状,以期为靶向治疗用放射性核素临床应用提供参考。

Targeted radiation therapy using radionuclides is a favored approach for treating tumors.This procedure involves the delivery of drugs to the lesion site via carriers or interventional methods,followed by the emission of radiation energy that selectively irradiates the lesion tissue.This approach minimizes damage to normal tissue and achieves the desired therapeutic effect.Factors such as the type of therapeutic radionuclide,radiation energy,physical half-life,method of preparation,and toxicity determine their clinical application.In this paper,the characteristics and clinical application of therapeutic radionuclides were reviewed to providing reference for the clinical application of targeted therapeutic radionuclides.