欣母沛对宫缩乏力性产后出血患者不良反应及效果的影响

Effect of Xinmupei on Adverse Reactions and Effects of Uterine Atony Induced Postpartum Bleeding

目的:探究并分析宫缩乏力性产后出血患者在欣母沛治疗后对临床不良反应的影响。方法:选择2021年12月—2022年12月邓州市人民医院收治的80例宫缩乏力性产后出血患者作为研究对象,按照随机分组方法将其划分为对照组和观察组,每组各40例。对照组患者采取传统缩宫素治疗,观察组患者则接受欣母沛治疗,观察两组患者疗效、阴道流血、凝血功能、生命体征、不良反应、生存质量情况。结果:观察组患者治疗总有效率水平高于对照组,差异有统计学意义(χ^(2)=4.114,P<0.05)。观察组患者产时及产后阴道流血量均低于对照组,差异有统计学意义(t=22.777、17.142、4.036、12.634,P<0.05)。两组患者分别实行护理干预后,凝血功能指标均有所变化,观察组患者血浆纤维蛋白原(FIB)数值更高,其余均以低水平呈现,差异有统计学意义(t=4.696、8.180、3.764、5.241,P<0.05)。观察组患者治疗期间的生命体征波动较为稳定,其中血压情况、心率、体温指标恢复效果明显高于对照组,差异有统计学意义(t=2.213、3.906、2.038、10.329,P<0.05)。两组患者护理干预后,测得生活质量得分有所提升,观察组患者更高,差异有统计学意义(t=19.422、10.104、7.611、13.312,P<0.05)。结论:欣母沛对宫缩乏力性产后出血的改善效果具有优势,且不良反应较少,用药安全性更高,患者更易接受。

Objective:To explore and analyze the influence of Xinmupei on clinical adverse reactions in patients with uterine atony induced postpartum bleeding.Methods:80 uterine atony induced postpartum bleeding patients admitted to the hospital from December 2021 to December 2022 were selected as the study subjects.According to the method of random grouping,they were divided into the control group and the observation group,with 40 cases in each group.The control group received traditional oxytocin treatment,while the observation group received Xinmupei treatment.Curative effect,vaginal bleeding,coagulation function,vital signs,adverse reaction,and survival quality of two groups were compared.Results:After evaluating the total effective rate,the observation group ranked at a higher level compared to the control group,and the difference was statistically significant(χ^(2)=4.114,P<0.05).The observation group showed lower vaginal bleeding during and after delivery compared to the control group,with statistically significant differences(t=22.777,17.142,4.036,12.634;P<0.05).After implementing nursing interventions,both groups showed changes in coagulation function indicators.The observation group showed higher levels of plasma fibrinogen(FIB),while the rest showed lower levels,with statistically significant differences(t=4.696,8.180,3.764,5.241;P<0.05).The fluctuation of vital signs during treatment in the observation group was relatively stable,with significantly higher recovery effects on blood pressure,heart rate,and body temperature indicators compared to the control group.The difference between the two groups was statistically significant(t=2.213,3.906,2.038,10.329;P<0.05).After nursing intervention,the quality of life scores between the groups were improved,and the observation group showed a higher score.The difference between the two groups was statistically significant(t=19.422,10.104,7.611,13.312;P<0.05).Conclusion:Xinmupei has advantages in improving the effect of uterine atony induced postpartum bleeding,with fewer adverse reactions,and higher safety and easier acceptance by patients.