中频脉冲电治疗对精神分裂症患者情感障碍的影响

Effect of Intermediate Frequency Electrotherapy on Affective Disorders in Patients with Schizophrenia

目的:观察中频脉冲电治疗对精神分裂症患者情感障碍的影响。方法:回顾性选取2023年4—8月宜春市第三人民医院收治的80例精神分裂症患者,按是否进行中频脉冲电治疗分成对照组(奥氮平片治疗)和观察组(中频脉冲电治疗联合奥氮平片治疗),各39、41例。观察患者情感症状程度、精神症状严重程度、临床疗效及不良反应情况。结果:治疗1、2、3、4个疗程后,观察组贝克-拉范森躁狂量表(BRMS)评分、汉密尔顿抑郁量表(HAMD)评分、汉密尔顿焦虑量表(HAMA)评分均低于对照组,差异均有统计学意义(P<0.05);治疗后,观察组阳性与阴性症状量表(PANSS)各项评分均低于对照组,差异均有统计学意义(P<0.05);观察组临床总有效率高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率相近,差异无统计学意义(P>0.05)。结论:中频脉冲电治疗联合奥氮平片治疗精神分裂症患者,对其情感障碍和精神症状改善显著,能提高其治疗效果,具有较高的安全性。

Objective:To observe the effect of intermediate frequency electrotherapy on affective disorders in patients with schizophrenia.Method:A retrospective study was conducted among 80 patients with schizophrenia who were admitted to the Third People's Hospital of Yichun City from April to August 2023.They were divided into control group(39 patients treated with Olanzapine Tablets)and observation group(41 patients treated with intermediate frequency electrotherapy and Olanzapine Tablets).The severity of affective symptoms,severity of mental symptoms,clinical efficacy and adverse reactions were observed.Result:After 1,2,3 and 4 courses of treatment,the Bech-Rafaelsen mania scale(BRMS)scores,Hamilton depression scale(HAMD)scores and Hamilton anxiety scale(HAMA)scores in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the scores for different items in positive and negative syndrome scale(PANSS)in the observation group were lower than those in the control group,with statistically significant differences(P<0.05).Clinical total effective rate in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).The incidence rates of adverse reactions in the two groups were close,the difference was not statistically significant(P>0.05).Conclusion:The combined treatment of intermediate frequency electrotherapy and Olanzapine Tablets can significantly improve affective disorders and mental symptoms in patients with schizophrenia,and improve the therapeutic effect,with high safety.