头皮针联合重复经颅磁刺激治疗儿童全面性发育迟缓临床研究

Clinical Study on Scalp Acupuncture Combined with Repetitive Transcranial Magnetic Stimulation for Global Developmental Delay in Children

目的:观察头皮针联合重复经颅磁刺激(rTMS)对儿童全面性发育迟缓(GDD)的临床疗效及对患儿认知、语言水平的影响。方法:将94例GDD患儿纳入研究,按随机数字表法分为研究组与对照组各47例,观察期间研究组、对照组各剔除1例,最终2组各纳入46例。对照组采取rTMS治疗,研究组在对照组基础上联合头皮针治疗。比较2组临床疗效、格塞尔(Gesell)发育量表评分、S-S语言发育迟缓评分及婴儿-初中生社会生活能力检查量表(S-M)评分。结果:治疗后,研究组总有效率为91.30%,对照组为76.09%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组适应性、粗大运动、精细运动、语言及个人-社会等Gesell各维度评分均较治疗前升高(P<0.05),且研究组各项评分均高于对照组(P<0.05)。治疗后,2组表达语言、构音障碍、接受语言能力等S-S语言发育迟缓各项评分均较治疗前升高(P<0.05),且研究组各项评分均高于对照组(P<0.05)。治疗后,2组独立生活、运动、交往、参加集体活动、作业、自我管理等各项S-M量表评分均较治疗前升高(P<0.05),且研究组各项评分均高于对照组(P<0.05)。结论:头皮针联合rTMS治疗儿童GDD临床疗效显著,可提高患儿智力发育、语言发育水平,从而提高患儿的社会生活能力。

Objective:To observe the clinical effect of scalp acupuncture combined with repetitive transcranial magnetic stimulation(rTMS)on global developmental delay(GDD)in children and its effects on their cognitive and language proficiency.Methods:A total of 94 cases of GDD children were enrolled in the study and divided into the study group and the control group according to the random number table method,with 47 cases in each group;during the observation period,one case was excluded in each group,and finally,there were 46 cases enrolled in each group.The control group was treated with rTMS,and the study group was additionally treated with scalp acupuncture based on the treatment of the control group.Clinical effects,as well as the scores of Gesell Developmental Assessment,S-S Language Delay,and Infants-Junior Middle School Students'Social-Life Abilities Scale(S-M scale)were compared between the two groups.Results:After treatment,the total effective rate was 91.30%in the study group and 76.09%in the control group,the difference being significant(P<0.05).After treatment,the scores of adaptive,gross motor,fine motor,language,and personal-social behavior in Gesell in the two groups were increased when compared with those before treatment(P<0.05),and the above scores in the study group were higher than those in the control group(P<0.05).After treatment,the scores of language expression,dysarthria,basic learning ability,and other domains in S-S in the two groups were increased when compared with those before treatment(P<0.05),and the above scores in the study group were higher than those in the control group(P<0.05).After treatment,the scores of general self-help,locomotion,communication,socialization skills,occupation,and self-direction in S-M scale in the two groups were increased when compared with those before treatment(P<0.05),and the above scores in the study group were higher than those in the control group(P<0.05).Conclusion:Scalp acupuncture combined with rTMS has significant clinical effects on the treatment of GDD in children,which can improve children's intellectual development and language development,thus to improve their social-life ability.