临床药师全程参与甲状腺功能亢进症伴肝损害患者药学实践的效果分析

Effect of Clinical Pharmacists'Full Participation in Pharmaceutical Practice in Patients with Hyperthyroidism and Liver Damage

目的:分析临床药师全程参与甲状腺功能亢进症(简称甲亢)伴肝损害患者药学实践的效果。方法:选取2022年1月—2023年12月徐州市沛县人民医院收治的甲亢伴肝损害患者76例为研究对象,采用随机数字表法分为对照组和观察组,各38例。对照组实施常规药学实践,观察组在对照组基础上实施临床药师全程参与的药学实践模式。对比两组服药依从性、不良反应发生率。结果:观察组服药总依从率高于对照组(P=0.033);观察组不良反应总发生率低于对照组(P=0.017)。结论:对甲亢伴肝损害患者采用临床药师全程参与药学实践模式可以提高其服药依从性,降低不良反应发生率。

Objective:To analyze the effect of clinical pharmacists'full participation in the pharmacy practice of patients with hyperthyroidism and liver damage.Methods:A total of seventy-six patients with hyperthyroidism and liver damage treated in Xuzhou Pei County People's Hospital from January 2022 to December 2023 were selected as the study objects,and were divided into control group and observation group by random number table method,with thirty-eight cases in each group.The control group implemented the routine pharmacy practice,and the observation group implemented the pharmacy practice mode with the full participation of clinical pharmacists on the basis of the control group.The medication compliance and incidence of adverse reactions were compared between the two groups.Results:The total compliance rate of observation group was higher than that of control group(P=0.033);the total incidence of adverse reactions in observation group was lower than that in control group(P=0.017).Conclusion:For patients with hyperthyroidism and liver damage,the full participation of clinical pharmacists in pharmaceutical practice can improve their medication compliance and reduce the incidence of adverse reactions.