八段锦功法对慢性阻塞性肺疾病患者去脂肪指数及焦虑抑郁状态的影响

Effects of Baduanjin in ameliorating FFMI,anti-depression and anti-anxiety in COPD patients

目的探讨八段锦功法指导慢性阻塞性肺疾病(COPD)患者去脂肪指数(FFMI)及焦虑状态的影响。方法将2021年7月至2023年7月新疆医科大学第一附属医院的154例COPD住院患者按照住院顺序分为基础治疗组和八段锦治疗组。基础治疗组给予常规治疗,不增加运动训练;八段锦治疗组在常规治疗基础上配合八段锦训练及专业运动指导。12周后2组患者采用体成分测定评估治疗前后中医症候评分、汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、慢性阻塞性肺疾病评估测试问卷(CAT),采用ELISA方法检测外周血肿瘤坏死因子样弱凋亡诱导因子(TWEAK)水平,比较治疗前后患者焦虑、抑郁状态改善情况。结果基础治疗组患者治疗后CAT评分减少,差异有统计学意义(P<0.05);中医症候评分、HAMA及HAMD评分无变化(P>0.05)。八段锦治疗组患者治疗后,中医症候评分、CAT评分、HAMA及HAMD评分减少,差异有统计学意义(P<0.05)。基础治疗组的肺功能变化不大(P>0.05)。八段锦治疗组患者第1秒用力呼气容积占用力肺活量的比例、第1秒用力呼气容积等指标治疗前后变化不大(P>0.05);呼气峰值流速占预计值百分比在治疗后较治疗前低,差异有统计学意义(P<0.05)。基础治疗组患者治疗前后FFMI无变化(P>0.05)。八段锦治疗组患者治疗前后FFMI升高,差异有统计学意义(P<0.05)。结论八段锦训练能够减轻COPD患者气道阻塞情况,提高肌肉质量,缓解患者焦虑抑郁状态,提高患者生活质量。

Objective To investigate the effect of Baduanjin training guidance on fat-free mass index(FFMI),quality of life and anxiety status in patients with chronic obstructive pulmonary disease(COPD).Methods One hundred and fifty-four patients with COPD in hospitalized were collected and divided into 2 groups:the basic group(Group B)and the Baduanjin training group(Group BBN)from July 2021 to July 2023 at the First Affiliated Hospital of Xinjiang Medical University,Group B was given routine rehabilitation training measures,and the Group BBN was given training guidance on the basis of routine rehabilitation.Lung function and body composition was measured,TCM syndrome score,Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD)scores and chronic obstructive pulmonary disease assessment questionnaire(CAT)were recorded and analyzed to compare the anxiety,depression and life quality improvement of 2 groups before and after the treatment.Results After 12 weeks of treatment,CAT score of patients in Group BBN was decreased,with statistical significance(P<0.05);TCM syndrome score,HAMA and HAMD score was showed no changing,without statistical significance(P>0.05).TCM syndrome score,CAT score,HAMA score and HAMD score of patients in Group BBN was decreased,with statistical significance(P<0.05).There was no significant difference in lung function in Group B(P>0.05).FEV 1/FVC%and FEV 1 in Group BN showed no significant difference after treatment(P>0.05),while PEF%was decreased after treatment in Group BBN(P<0.05).There was no significant difference in FFMI in Group B(P>0.05),while it was improved in Group BBN,the difference has statistically significant(P<0.05).Conclusions Baduanjin training could improve airway obstruction,increase the level of muscle mass,relieve the condition of anxiety and depression,and improve the quality of life in patients with COPD.