术中干预对结直肠癌患者术后住院期间发生下肢深静脉血栓的影响

Effect of intraoperative intervention on the occurrence of lower extremity deep vein thrombosis in patients with colorectal cancer during hospitalization after surgery

目的探讨术中干预对结直肠癌患者术后住院期间发生下肢深静脉血栓(DVT)的影响。方法收集2021年11月至2023年7月亳州市人民医院接受手术治疗的121例结直肠癌患者的临床资料,按照是否接受了预防下肢DVT的术中干预措施将患者分为观察组(n=61)和对照组(n=60)。比较两组患者的手术相关指标、住院期间治疗情况及术后住院期间结局。结果观察组患者术中低体温的发生率低于对照组患者,差异有统计学意义(P﹤0.05);两组患者的手术时间、术中出血量、术中输血比例、术后穿弹力袜和应用空气波压力治疗系统的比例比较,差异均无统计学意义(P﹥0.05)。住院期间,共6例患者发生下肢DVT,均发生于对照组。两组患者术后均未发生明显的出血和感染。观察组患者术后D-二聚体水平明显低于对照组患者,差异有统计学意义(P﹤0.01);两组患者术后凝血酶原时间、活化部分凝血活酶时间、白细胞计数、血红蛋白水平比较,差异均无统计学意义(P﹥0.05)。结论术中干预措施可以安全、有效地降低结直肠癌患者术后下肢DVT的发生率,值得临床推广。

Objective To investigate the effect of intraoperative intervention on the occurrence of deep vein thrombosis(DVT)in the lower extremity of colorectal cancer patients during postoperative hospitalization.Method The clinical data of 121 colorectal cancer patients who underwent surgical treatment at Bozhou People's Hospital from November 2021 to July 2023 were collected,and the patients were divided into observation group(n=61)and control group(n=60)based on whether they received intraoperative intervention to prevent lower extremity DVT.The surgical related indicators,treatment status during hospitalization,and postoperative hospitalization outcomes between two groups of patients were compared.Result The incidence of intraoperative hypothermia in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05);there were no statistically significant differences in the surgical time,intraoperative blood loss,intraoperative blood transfusion ratio,postoperative wearing of elastic stockings,and application of air wave pressure therapy system between the two groups of patients(P>0.05).During hospitalization,a total of 6 cases of lower extremity DVT occurred in colorectal cancer patients,all of which occurred in the control group.There was no significant bleeding or infection in both groups after surgery.The postoperative D-dimer level in the observation group was significantly lower than those in the control group,and the difference was statistically significant(P<0.01);there were no statistically significant differences in postoperative prothrombin time,activated partial thromboplastin time,white blood cell count,and hemoglobin levels between the two groups of patients(P>0.05).Conclusion Intraoperative intervention can safely and effectively reduce the incidence of postoperative lower extremity DVT in patients with colorectal cancer,and is worthy of clinical promotion.