血清C肽与糖化血红蛋白检验应用于糖尿病诊断中的准确性探讨

Accuracy of Serum C-peptide and Glycosylated Hemoglobin Test in the Diagnosis of Diabetes Mellitus

目的探讨血清C肽、糖化血红蛋白检验在糖尿病诊断中的准确性。方法选取2022年8月—2023年12月于咸宁市咸安区妇幼保健院就诊的疑似糖尿病患者120例,均实施血清C肽、糖化血红蛋白检验,以临床综合诊断结果作为金标准,比较血清C肽、糖化血红蛋白单一检验及联合检验的诊断效能(准确度、特异度、灵敏度)。结果血清C肽、糖化血红蛋白联合检测的准确度、特异度、灵敏度均高于单一检测,差异有统计学意义(P均<0.05)。结论在糖尿病诊断过程中,血清C肽与糖化血红蛋白联合检验的诊断效能更高。

Objective To investigate the accuracy of serum C-peptide and glycosylated hemoglobin test in the diagno⁃sis of diabetes mellitus.Methods A total of 120 patients with suspected diabetes who were treated in Xian'an District Maternal and Child Health Hospital from August 2022 to December 2023 were selected.Serum C-peptide and glyco⁃sylated hemoglobin tests were performed.The clinical comprehensive diagnosis results were used as the gold standard to compare the diagnostic efficacy(accuracy,specificity,sensitivity)of single test and combined test of serum C-peptide and glycosylated hemoglobin.Results The accuracy,specificity and sensitivity of serum C-peptide and glyco⁃sylated hemoglobin combined detection were higher than those of the single detection,and the differences were statistically significant(all P<0.05).Conclusion In the process of diabetes diagnosis,the diagnostic efficacy of the combined test of serum C-peptide and glycosylated hemoglobin are high.