通心络胶囊治疗冠心病稳定型心绞痛气虚血瘀络阻证临床效果研究进展

Research Progress on the Clinical Effect of Tongxinluo Capsule on Qi Defi⁃ciency and Blood Stasis and Collateral⁃obstruction Syndrome of Stable An⁃gina Pectoris of Coronary Heart Disease

冠心病在临床上是一种常见的多发疾病,主要的发病群体是中老年人,一旦发病就会严重影响患者的日常生活,增加残疾和死亡的风险。而稳定型心绞痛是冠心病中常见的一种类型,主要是由心肌血氧供应不足导致的,若是不及时予以有效治疗,就会造成心功能逐渐下降,在急性发作期间还会威胁患者的生命安全。现阶段临床治疗稳定型心绞痛大多是稳定冠状动脉粥样硬化斑块、改善肌缺血缺氧,从而减轻心肌组织的损伤,防止心功能降低。以往临床治疗大多选择常规西药干预,可是部分患者由于长期用药产生耐药性,造成临床疗效一般,故需要选择一种更加科学有效的治疗手段改善患者预后。中医认为,稳定型心绞痛的病机与气滞、血瘀有着密切关系,治疗原则为活血化瘀和行气止痛,而通心络胶囊是治疗心血管疾病常用的中药,也在冠心病稳定型心绞痛气虚血瘀络阻证的临床治疗中被广泛应用并认可。

Coronary heart disease(CHD)is a common disease in clinical practice,mainly affecting middle-aged and elderly people.Once it occurs,it will seriously threaten daily life of patients,and increase the risk of disability and death.Stable angina pectoris is one of the most common types of CHD,mainly caused by insufficient myocardial oxygen supply.If not treated effectively in a timely manner,it will gradually lead to a decline in heart function and even threaten the patient's life safety during acute attacks.At present,the clinical treatment of stable angina pectoris is mostly to stabilize coronary athero-sclerotic plaque,and alleviate myocardial ischemia and hypoxia,so as to reduce the damage of myocardial tissue and prevent the decrease of cardiac function.In the past,conventional western medicine intervention was mostly used in clinical treat-ment,but some patients developed drug resistance due to long-term drug use,resulting in general clinical efficacy.Therefore,it is necessary to choose a more scientific and effective treatment to improve the prognosis of patients.TCM practitioners be-lieve that the pathogenesis of stable angina pectoris is closely related to qi stagnation and blood stasis,so the treatment princi-ple is to promote blood stasis and qi analgesia.Tongxinluo capsule is a commonly used traditional Chinese medicine in the clinical treatment of cardiovascular diseases,and is also widely used and recognized in the clinical treatment of stable angina pectoris of CHD with qi deficiency,blood stasis,and collaterals obstruction syndrome.