骨质疏松与精神疾病相关性研究进展

The correlation between osteoporosis and neuropsychiatric disorders

骨质疏松症(osteoporosis)和精神疾病(neuropsychiatric disorders)是目前影响人类健康的重要躯体和精神系统疾病,且近年来发病率呈上升趋势,对社会经济发展及医疗卫生服务影响产生重大影响,并逐渐成为当今世界备受关注的公共卫生问题。骨质疏松症与精神疾病在一定程度上存有双向联系并相互影响。已有证据证明现在包括抑郁症、帕金森病、阿尔茨海默症等多种神经精神疾病与骨质疏松症和脆性骨折的发生发展高度相关。作为老年人群中最常见的慢性退变性疾病,骨质疏松症与神经精神疾病并存的同时,在一定程度上存有双向联系。本文对近年来关于骨质疏松与精神疾病相关性研究进行了文献复习并做一综述总结。

Osteoporosis and neuropsychiatric disorders are important physical and mental system diseases that affect human health.In recent years,the incidence rate is on the rise,which has a significant impact on socio-economic development and medical and health services,and has gradually become a public health problem of concern in the world.Osteoporosis and mental disorders have a two-way relationship and mutual influence to a certain extent.There is evidence that various neurological and psychiatric disorders such as depression,Parkinson's disease,and Alzheimer's disease are highly correlated with the occurrence and development of osteoporosis and fragility fractures.As the most common chronic degenerative disease among the elderly population,evidence from epidemiological and clinical studies indicates that osteoporosis coexists with neurological and psychiatric disorders,and there is a two-way relationship to some extent.This article reviews and summarizes the literature on the correlation between osteoporosis and mental disorders in recent years.