摘要
Apoptosis regulator Bcl-extra(Bcl-x),also named BCL2L or BCL2L1,is a typical example of apoptotic response gene impacted by splicing.It is an essential member of B-cell lymphoma 2(Bcl-2)apoptosis family that regulates cell fate^([1,2]).Bcl-x nascent transcripts are alternatively spliced and mainly encode two antagonistic isoforms.
基金
National Key R&D Project of Chinese Ministry of Science and Technology(2018YFE0205100)
Key Program of National Natural Science Foundation of China(11875299)
National Natural Science Foundation of China(11675234)。