睡眠状态干预护理对宫颈癌切除术患者免疫功能的影响

Impact of sleep state intervention nursing on immune function of patients undergoing cervical cancer excision

目的探讨睡眠状态干预护理对宫颈癌切除术患者免疫功能的影响。方法选取西安交通大学第一附属医院榆林医院于2021年10月至2023年10月收治的82例宫颈癌患者进行随机对照试验,所有患者均接受子宫切除术与淋巴结清扫,随机数字表法分为对照组和观察组,每组41例。对照组采用常规护理方法,观察组在对照组的基础上联合睡眠状态干预,两组均干预1个月。比较两组患者术后恢复情况,采用视觉模拟量表(VAS)评估两组患者术后1 d、术后1周、术后1个月的疼痛情况,匹兹堡睡眠质量量表(PSQI)评估患者干预前和干预1个月后的睡眠状况,测定干预前后的血清免疫球蛋水平,并利用世界卫生组织生存质量测定量表(WHOQOL-BREF)从生理领域、心理领域、社会领域、环境领域评估患者干预前后的生活质量。采用t检验、χ^(2)检验进行统计比较。结果观察组患者术后下床活动时间、排气时间、排便时间和住院时间分别为(11.62±1.45)h、(29.88±4.01)h、(2.90±0.47)d、(6.61±1.13)d,对照组分别为(19.04±2.38)h、(56.72±7.19)h、(4.26±0.63)d、(10.84±2.45)d,两组比较差异均有统计学意义(均P<0.001)。术后1 d、术后1周、术后1个月观察组的VAS评分均低于对照组,差异均有统计学意义(均P<0.001)。干预1个月,观察组的PSQI评分低于对照组,免疫球蛋白水平和生活质量评分高于对照组,差异均有统计学意义(均P<0.05)。结论睡眠状态干预有助于宫颈癌切除术患者的术后恢复,能提高免疫功能、睡眠质量和生活质量。

Objective To investigate the impact of sleep state intervention nursing on the immune function of patients undergoing cervical cancer excision.Methods Eighty-two patients with cervical cancer treated at Yulin Hospital,First Hospital,Xi'an Jiaotong University from October 2021 to October 2023 were selected for the randomized controlled trial.All the patients underwent hysterectomy and lymph node dissection.They were divided into a control group and an observation group by the random number table method,with 41 patients in each group.The control group received conventional nursing;in addition,the observation group received combined sleep state intervention.Both groups were intervened for one month.The postoperative recovery conditions of the two groups were compared.The Visual Analogue Scale(VAS)was use to evaluate the patients'pain in both groups 1 d,1 week,and 1 month after the operation.The patients'sleep quality was evaluated by the Pittsburgh Sleep Quality Index(PSQI)before and 1 month after the intervention.The serum levels of immunoglobulins were measured before and after the intervention.The patients'quality of life before and after the intervention was assessed in the physical,psychological,social,and environmental domains using the World Health Organization Quality of Life-BREF Scale(WHOQOL-BREF).t test andχ^(2)test were used for statistical comparison Results The postoperative time for off-bed activity,time to first flatus,time to first bowel movement,and hospital stay in the observation group were shorter than those in the control group[(11.62±1.45)h vs.(19.04±2.38)h,(29.88±4.01)h vs.(56.72±7.19)h,(2.90±0.47)d vs.(4.26±0.63)d,and(6.61±1.13)d vs.(10.84±2.45)d],with statistical differences(all P<0.001).The VAS scores of the observation group were lower than those of the control group 1 day,1 week and 1 month after surgery,and the differences were statistically significant(all P<0.001).One month after the intervention,the scores of PSQI and life quality and levels of immunoglobulins in the observation group were better than those in the control group,with statistical differences(all P<0.05).Conclusion Sleep state intervention can aid in the postoperative recovery of patients taking cervical cancer excision,and improve their sleep quality,immune function,and life quality.