腹腔镜下胆囊切除术治疗急性结石性胆囊炎的效果分析

Effect Analysis of Laparoscopic Cholecystectomy in the Treatment of Acute Calculous Cholecystitis

目的:探究腹腔镜下胆囊切除术与传统胆囊切除术在急性结石性胆囊炎中应用效果。方法:采用抽签法,选取2021年10月~2023年10月本院50例急性结石性胆囊炎患者,将其分为对照组(行传统胆囊切除术)和观察组(行腹腔镜下胆囊切除术),每组25例。对比两组手术相关指标、疼痛情况、炎症因子及并发症发生率。结果:观察组手术相关指标均优于对照组。相较于对照组,观察组患者术后3h、术后6h、术后12h、术后24h视觉模拟评分法评分均更低(P<0.05)。相较于对照组,观察组患者的Toll样受体-4、C反应蛋白水平更低(P<0.05)。观察组并发症(切口感染、肺部感染、胆管损伤、胆漏情况)总发生率12.00%低于对照组的28.00%(P<0.05)。结论:在急性结石性胆囊炎患者的治疗中采用腹腔镜下胆囊切除术效果明显优于传统胆囊切除术,不仅可以改善患者的临床指标,减少住院时间,还可以改善患者的炎症因子,且不良反应较少,具有安全性。

Objective:To explore the application effects of laparoscopic cholecystectomy(LC)and traditional cholecystectomy(CC)in acute calculous cholecystitis.Methods:Using a lottery method,50 patients with acute calculous cholecystitis in our hospital from October 2021 to October 2023 were selected and divided into a control group(CC)and an observation group(LC),with 25 cases in each group.Compare the two groups of surgical related indicators,pain status,inflammatory factors,and incidence of complications.Results:The observation group had better surgical related indicators than the control group.Compared to the control group,the observation group had lower VAS scores at 3 hours,6 hours,12 hours,and 24 hours after surgery(P<0.05).Compared to the control group,the TLR-4 and CRP levels in the observation group were lower(P<0.05).The total incidence of complications(incision infection,lung infection,bile duct injury,bile leakage)in the observation group was 12.00%,lower than that in the control group(28.00%,P<0.05).Conclusion:LC surgery is significantly better than CC surgery in the treatment of acute calculous cholecystitis patients.It can not only improve clinical indicators,reduce hospital stay,but also improve inflammatory factors.With fewer adverse reactions,it is safe.