经尿道前列腺等离子电切术对良性前列腺增生患者尿道功能及氧化应激指标的影响分析

Effect of Transurethral Plasma Resection of Prostate on Urethral Function and Oxidative Stress Index in BPH Patients

目的:研究经尿道前列腺等离子电切术(PKRP)对良性前列腺增生(BPH)患者尿道功能及氧化应激指标的影响并予以分析。方法:选取江西省抚州市乐安县人民医院从2021年1月~2023年3月收治的69例BPH患者作为研究对象。将其以电脑编号随机法分为观察组(n=34)及对照组(n=35)。观察组选用PKRP治疗,对照组则选用经尿道前列腺切除术(TURP)治疗。对比两组各项围术期指标,尿道功能指标,氧化应激指标,前列腺症状及性功能。结果:观察组术中失血量少于对照组,而尿管留置天数及住院天数均短于对照组(均P<0.05)。术后半年两组各项尿道功能指标水平及国际前列腺症状量表(IPSS)、国际勃起功能指数5项问卷(IIEF-5)评分较术前均改善,且观察组改善幅度优于对照组(均P<0.05)。术后3d两组各项氧化应激指标水平较术前均改善,且观察组改善幅度优于对照组(均P<0.05)。结论:PKRP治疗BPH患者的效果较佳,可促进患者尿道功能的恢复,减轻氧化应激反应,改善前列腺症状与性功能。

Objective:To investigate the effects of transurethral plasmotomy of prostate(PKRP)on urethral function and oxidative stress indexes in patients with benign prostatic hyperplasia(BPH).Methods:69 patients with BPH who were admitted to People’s Hospital of Le’an County,Fuzhou City,Jiangxi Province from January 2021 to March 2023 were selected as the study objects.They were randomly divided into observation group(n=34)and control group(n=35)by computer numbering.Observation group was treated with PKRP,control group was treated with transurethral resection of prostate(TURP).Perioperative indexes,urethral function indexes,oxidative stress indexes,prostate symptoms and sexual function were compared between the two groups.Results:The intraoperative blood loss in observation group was less than that in control group,and the days of urinary catheter indwelling and hospitalization were shorter than those in control group(all P<0.05).The levels of urethral function indexes and the scores of International Prostatic Symptom Scale(IPSS)and International Erectile Function Index(IIEF-5)were improved in both groups half a year after surgery,and the improvement of observation group was better than that of control group(all P<0.05).The levels of oxidative stress indexes in both groups were improved after 3 days,and the improvement in observation group was better than that in control group(all P<0.05).Conclusion:PKRP is effective in the treatment of BPH patients,which can promote the recovery of urethral function,reduce the oxidative stress reaction.