双歧杆菌的有益代谢物生成途径及其健康作用和应用

Production Pathways,Health Benefits and Application of Beneficial Metabolites of Bifidobacterium

益生菌被定义为是一类安全、无致病性且对宿主健康有益的活性微生物,双歧杆菌是其中最值得研究的一种肠道益生菌。近年来关于双歧杆菌代谢物及健康机制方面的研究受到重视,双歧杆菌能够通过发酵利用营养物质产生不同种类的有益代谢产物,主要包括短链脂肪酸、酚类物质、氨基酸及维生素等代谢物。这些有益代谢产物的生成涉及一系列复杂的酶和底物代谢途径,且对宿主健康具有积极的影响,在益生菌制剂、食品添加剂等方面具有应用前景。双歧杆菌的发酵产物正在逐渐应用于产品开发,例如益生菌饮料、乳酸菌酸奶和功能性保健品。因此,本文简述双歧杆菌有益代谢物生成途径及其健康作用和应用,旨在为双歧杆菌代谢物在食品、医药、保健品等领域的开发和应用提供参考。

Probiotics are defined as a group of active microorganisms that are safe,non-pathogenic and beneficial to host health,and Bifidobacterium is one of the most studied intestinal probiotics.In recent years,research on the metabolites and health-promoting mechanisms of Bifidobacterium has attracted attention.This probiotic is able to utilize nutrients through fermentation to produce different types of beneficial metabolites such as short-chain fatty acids,phenolics,amino acids,and vitamins.A series of complex metabolic processes are involved in the production of these advantageous metabolites,which have a favorable effect on host health and show promise for applications in probiotic preparations and food additives.Bifidobacterium fermented products are progressively being utilized in the development of probiotic drinks,yogurt and functional foods.Therefore,this article briefly describes the production pathways,health benefits and application of beneficial metabolites of Bifidobacterium,aiming to provide a reference for the development and application of Bifidobacterium metabolites in the food,pharmaceutical and nutraceutical fields.