摘要
研究以多种简单易得的烯烃与苯硫酚为原料,以高产率合成2类不同类型的β-氯代硫醚及β-羟基取代硫醚.反应通过选择不同的反应溶剂,实现不同产物的选择性合成.当以无水乙腈为溶剂时,可以中等至高的收率生成得到β-氯代硫醚;而在溶剂二甲基亚砜中,则可选择性地生成β-羟基取代硫醚.该反应有较好的底物适应性,官能团容忍度,并具有操作简便、反应条件温和等优点.
In this work,two different types ofβ-substituted thioethers are synthesized with high yields from simple alkenes and thiophenols.The products of this reaction could be controlled by the solvent.When anhydrous acetonitrile was used as the solvent,β-chloro-substituted thioethers were obtained in medium to high yields.When using dimethyl sulfoxide,β-hydroxyl-substituted thioethers generated alternatively.Moreover,this novel approach features the advantages of wide substrate scope,good functional group tolerance,simple operation,and mild response conditions.
作者
李春生
陈耀杨
叶非华
LI Chunsheng;CHEN Yaoyang;YE Feihua(School of Environmental and Chemical Engineering,Zhaoqing University,Zhaoqing,Guangdong 526061,China)
出处
《肇庆学院学报》
2024年第5期78-83,97,共7页
Journal of Zhaoqing University
基金
广东省基础与应用基础研究基金项目(2020A1515111156)
大学生创新创业训练计划项目(202310580015)
肇庆学院2022年校级科研基金项目(QN202229)
佛山市教育局高校教师特色创新研究项目(2021JNHB16)。
关键词
无金属催化
烯烃
双官能团化
β-取代硫醚
结构表征
metal-free catalyzed
alkenes
di-functionalization
β-substituted thioethers
structural character-ization.