胃肠镜检查联合血清CEA水平检测对消化道肿瘤早期诊断的价值分析

Analysis of the value of gastroscopy combined with serum CEA level test in early diagnosis of gastrointestinal tumors

目的探究消化道肿瘤患者应用胃肠镜检查联合血清癌胚抗原(CEA)水平检测的早期诊断价值。方法收集80例疑似为消化道肿瘤患者纳入研究,对患者均采用胃肠镜检查,并进行血清CEA水平检测。分析单独血清CEA水平检测、胃肠镜检查的诊断效能(灵敏度、特异度)及血清CEA水平检测联合胃肠镜检查的诊断效能。结果80例患者经病理确诊为消化道恶性肿瘤患者60例,其余20例为非消化道恶性肿瘤患者。60例消化道恶性肿瘤中胃癌15例,大肠癌30例,食管癌11例,小肠癌4例。胃肠镜检查灵敏度为91.7%,特异度为75.0%;血清CEA水平检测灵敏度为96.7%,特异度为90.0%。并联公式计算结果显示,灵敏度为99.7%,特异度为67.5%;串联公式计算结果显示,灵敏度为88.7%,特异度为97.5%。结论消化道肿瘤患者采用胃肠镜检查与血清CEA水平诊断具有一定价值,但均存在局限性,两项联合诊断可有效提高消化道肿瘤早期诊断准确性,值得临床推广应用。

Objective To explore the value of gastroscopy combined with serum carcinoembryonic antigen(CEA)level test in early diagnosis of gastrointestinal tumors.Methods 80 patients with suspected gastrointestinal tumors were included in the study,and all patients underwent gastroscopy examination and serum CEA levels test.The diagnostic efficacy(sensitivity and specificity)of serum CEA level test and gastroenteroscopy alone and in combination was analyzed.Results Of the 80 patients,60 cases were pathologically diagnosed as malignant gastrointestinal tumors,and the remaining 20 cases were non-malignant gastrointestinal tumors.Among the 60 cases of malignant gastrointestinal tumors,there were 15 cases of gastric cancer,30 cases of colorectal cancer,11 cases of esophageal cancer,and 4 cases of small intestine cancer.The sensitivity of gastroscopy was 91.7%and the specificity was 75.0%;the sensitivity of serum CEA test was 96.7%and the specificity was 90.0%.The results of the parallel formula showed that the sensitivity was 99.7%and the specificity was 67.5%;the results of the series formula showed that the sensitivity was 88.7%and the specificity was 97.5%.Conclusion Gastroscopy and serum CEA level test have certain value for patients with gastrointestinal tumors,but both have limitations.The combined diagnosis of the two can effectively improve the accuracy of early diagnosis of gastrointestinal tumors.It is worthy of clinical promotion and application.