袁兴石验方济川延寿膏治疗老年功能性便秘脾肾阳虚证的临床效果研究

Clinical effects of Yuan Xingshi's prescription Jichuan Yanshou Ointment in the treatment of functional constipation with spleen and kidney yang deficiency syndrome in the elderly

目的探究袁兴石验方济川延寿膏治疗老年功能性便秘脾肾阳虚证的临床效果。方法选择70例老年功能性便秘脾肾阳虚证患者作为研究对象,根据随机数字表法分为对照组与观察组,各35例。观察组给予袁兴石验方济川延寿膏治疗,对照组给予乳果糖口服溶液治疗。比较两组治疗效果、中医证候积分、生活质量及不良反应发生情况。结果观察组患者治疗总有效率97.14%明显高于对照组的80.00%(P<0.05)。治疗后观察组患者大便干、排便困难、脉沉主症中医证候积分及小便清长、舌淡苔白、腹中痛冷次症中医证候积分均明显低于对照组(P<0.05)。治疗后,两组患者的生活质量评分均高于治疗前,且观察组患者的生活质量评分(88.14±5.62)分显著高于对照组的(74.05±4.37)分(P<0.05)。观察组与对照组不良反应比较(2.86%VS 5.71%)无差异(P>0.05)。结论在老年功能性便秘脾肾阳虚证治疗中,袁兴石验方济川延寿膏可以有效提高治疗效果,且患者中医证候积分改善显著,生活质量明显提高,用药安全可靠,有显著应用价值,值得推广应用。

Objective To explore the clinical effects of Yuan Xingshi's prescription Jichuan Yanshou Ointment in the treatment of functional constipation with spleen and kidney yang deficiency syndrome in the elderly.Methods 70 elderly patients with functional constipation with spleen and kidney yang deficiency syndrome were selected as the study subjects,and were divided into a control group and an observation group based on random number table method,with 35 cases in each group.The observation group was treated with Yuan Xingshi's prescription Jichuan Yanshou Ointment,and the control group was treated with lactulose oral solution.The therapeutic effect,traditional Chinese medicine syndrome score,quality of life and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of 97.14%in the observation group was significantly higher than 80.00%in the control group(P<0.05).After treatment,the traditional Chinese medicine syndrome scores for the main symptoms of dry stool,difficulty defecation,deep pulse,and the traditional Chinese medicine syndrome scores for minor symptoms of clear urination,pale tongue with whitish coating,abdominal pain and coldness in the observation group were significantly lower than those in the control group(P<0.05).After treatment,the quality of life score of the two groups was higher than that before treatment,and the quality of life score of(88.14±5.62)points in the observation group was significantly higher than(74.05±4.37)points in the control group(P<0.05).There was no difference in adverse reactions between the observation group and the control group[2.86%VS 5.71%](P>0.05).Conclusion In the treatment of functional constipation with spleen and kidney yang deficiency syndrome in the elderly,Yuan Xingshi's prescription Jichuan Yanshou Ointment can effectively improve the therapeutic effect,traditional Chinese medicine syndrome score,and the quality of life significantly.The medication is safe and reliable,and has significant application value,which is worthy of promotion and application.