急性大核心脑梗死血管内治疗研究进展

Recent advances in endovascular treatment for acute large-core cerebral infarction

缺血性卒中(即脑梗死)是致死率和致残率均较高的疾病,而大核心脑梗死是较为严重的一种。早期血管内治疗是目前主要治疗手段之一。近期有多项关于大核心脑梗死血管内治疗的临床研究结果发表,包括RESCUE-Japan LIMIT、ANGEL-ASPECT、SELECT 2、TENSION、LASTE研究,但也存在诸多疑惑。本文将从大核心脑梗死研究现状、5项临床研究特点等方面展开,就急性大核心脑梗死血管内治疗研究进展作一述评。

Ischemic stroke is a disease with high mortality and morbidity rates,and large-core cerebral infarction represents a particularly severe form of the disease.Currently,early endovascular treatment is one of the main treatment modalities.Recent clinical studies on endovascular therapy for large-core cerebral infarction,including RESCUE-Japan LIMIT,ANGEL-ASPECT,SELECT 2,TENSION,and LASTE,have been published,but some details still remain uncertainly.This paper will provide some narrations and comments by reviewing the research status and the characters of these five trials about large-core cerebral infarction.