摘要
Nesfatin-1是一种神经肽类激素,已知的生物学作用包括抑制食物摄入、调节血糖血脂代谢、促进细胞凋亡、抗炎、抗肿瘤等。糖代谢是机体能量来源的重要途径。目前的研究已证实Nesfatin-1可通过抑制摄食、调节酶活性、改善胰岛素抵抗等途径影响糖代谢,但是结论并不完全一致。探讨Nesfatin-1与糖代谢的关系可为糖代谢障碍相关疾病的诊断和治疗提供新的思路。
Nesfatin-1 is a neuropeptide hormone known for its biological functions,including inhibiting food intake,regulating glucose and lipid metabolism,promoting apoptosis,and providing anti-inflammatory and anti-tumor effects.Glucose metabolism is a crucial pathway for the body’s energy supply.Current research has demonstrated that Nesfatin-1 can affect glucose metabolism through various mechanisms,such as inhibiting food intake,regulating enzyme activity,and improving insulin resistance,though the findings are not entirely consistent.Investigating the relationship between Nesfatin-1 and glucose metabolism may offer new insights into the diagnosis and treatment of diseases related to glucose metabolism disorders.
作者
曹云婷
王玮
CAO Yunting;WANG Wei(Department of Endocrinology,First Affiliated Hospital of Baotou Medical College,Baotou Inner Mongolia Autonomous Region 014010,China)
出处
《中南大学学报(医学版)》
CAS
CSCD
北大核心
2024年第6期832-838,共7页
Journal of Central South University :Medical Science
基金
内蒙古自治区高等学校科学研究项目(NJZY21058)。