高原地区慢性萎缩性胃炎胃镜分型及临床特点回顾性分析

Retrospective analysis of the gastroscopic typing and clinical features of chronic atrophic gastritis in the upland areas

目的探讨高原地区慢性萎缩性胃炎(chronic atrophic gastritis,CAG)患者的发病特点、病理改变、胃镜分型。方法回顾性分析西藏自治区人民医院2020年1月至2023年3月收治的464例CAG患者的临床资料。结果高原地区CAG患者年龄分布以>50~60岁为主,各年龄组间性别的分布差异无统计学意义(P>0.05);临床症状以乏力(49.57%)、腹胀(44.61%)、腹痛(40.30%)多见;胃镜分型以C_(2)型(70.26%)较多见;胃镜像以胃黏膜红白相间,以白为主多见,不同海拔高度CAG患者胃镜像中仅CAG伴糜烂差异有统计学意义(P<0.05);病理特点以中度萎缩,轻、中度肠化多见。结论高原地区胃镜分型以C_(2)型为主,海拔的升高对CAG患者病理进程有一定的影响,应重视CAG的发病特点,降低患病风险。

Objective To investigate the pathogenetic features,mucosal changes,and gastroscopic staging of chronic atrophic gastritis(CAG)in upland areas.Methods Retrospective analysis of the clinical data of 464 patients with CAG admitted to the People′s Hospital of Tibet Autonomous Region from Jan.2020 to Mar.2023.Results The age distribution of CAG in the upland areas was mainly>50-60 years old,and there was no significant difference in the distribution of gender among the age groups(P>0.05);clinical symptoms were mainly weakness(49.57%),abdominal distension(44.61%)and abdominal pain(40.30%);gastroscopic typing was more common in type C_(2)(70.26%);gastroscopic images were mainly white with red and white gastric mucosa,and CAG at different altitudes.Gastroscopic images of patients with CAG at different altitudes were statistically significant(P<0.05);pathological features were moderate atrophy and mild to moderate intestinalization.Conclusion Gastroscopic staging is predominantly type C_(2)in the highlands.The rise in altitude has an impact on the pathological process of CAG patients,and attention should be paid to the pathogenetic characteristics of CAG to reduce the risk of the disease.