秋水仙碱抗炎在缺血性卒中预防中的作用

Anti-inflammatory role of colchicine in the prevention of ischemic stroke

炎症与缺血性卒中的发病和复发有关,患有冠状动脉疾病并接受秋水仙碱治疗的患者血管事件发生率降低。然而,秋水仙碱抗炎在预防复发性卒中方面的有效性和安全性尚不明确。文章对秋水仙碱的相关作用机制及其在缺血性卒中预防中的作用进行了综述,期望为缺血性卒中的二级预防提供参考依据。

Inflammation is associated with the occurrence and recurrence of ischemic stroke,and patients with coronary artery disease who receive colchicine treatment have a lower incidence of vascular events.However,the efficacy and safety of anti-inflammatory therapy with colchicine in preventing recurrent stroke is unclear.This article reviews the relevant mechanisms of action of colchicine and its role in the prevention of ischemic stroke,aiming to provide reference for the secondary prevention of ischemic stroke.