七氟醚联合瑞芬太尼在腹腔镜子宫肌瘤切除术中的应用效果

Application effect of Sevoflurane combined with Remifentanil in lapa-roscopic myomectomy

目的分析七氟醚联合瑞芬太尼在腹腔镜子宫肌瘤切除术中的应用效果。方法选取2022年3月至2023年3月于同济大学附属上海市东方医院胶州医院行腹腔镜子宫肌瘤切除术的50例患者作为研究对象,按照随机数字表法分为对照组(50例)与观察组(50例)。对照组采用丙泊酚联合瑞芬太尼麻醉,观察组采用七氟醚联合瑞芬太尼麻醉。比较两组麻醉效果、不良反应发生情况及血流动力指标。结果观察组苏醒时间[(5.13±1.62)min]、自主呼吸时间[(5.27±1.29)min]、言语应答时间[(8.36±2.63)min]及定向力恢复时间[(19.52±1.39)min]均较对照组短[(9.37±2.54)、(9.55±3.02)、(13.02±4.05)、(27.69±3.27)min],差异有统计学意义(P<0.05)。观察组不良反应总发生率(4.00%)低于对照组(24.00%),差异有统计学意义(P<0.05)。两组气腹后10 min(T1)、对照组缝合时(T2)的心率及平均动脉压均较麻醉前高,但观察组T1、T2心率及平均动脉压均低于对照组,差异有统计学意义(P<0.05)。结论七氟醚联合瑞芬太尼在腹腔镜子宫肌瘤切除术中的应用效果较好,可促进术后恢复,减少不良反应发生,稳定血流动力学指标,值得推广和使用。

Objective To analyze the application effect of Sevoflurane combined with Remifentanil in laparoscopic myomectomy.Methods A total of 50 patients who underwent laparoscopic myomectomy in Jiaozhou Hospital,Shanghai Dongfang Hospital Affiliated to Tongji University from March 2022 to March 2023 were selected as the study objects.All the patients were divided into the control group(50 cases)and the observation group(50 cases)using the random number table method.The control group received P ropofol combined with Remifentanil anesthesia,while the observation group received Sevoflurane combined with Remifentanil anesthesia.The anesthesia effects,incidence of adverse reactions,and hemodynamic indicators of the two groups were compared.Results The awakening time([5.13±1.62]minutes),spontaneous breathing time([5.27±1.29]minutes),verbal response time([8.36±2.63]minutes),and orientation recovery time([19.52±1.39]minutes)of the observation group were shorter than those of the control group([9.37±2.54],[9.55±3.02],[13.02±4.05],and[27.69±3.27]minutes),and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group(4.00%)was lower than that in the control group(24.00%),and the difference was statistically significant(P<0.05).The heart rate and mean arterial pressure at 10 minutes after pneumoperitoneum(T1)of the two groups and during suturing(T2)of the control group were higher than those before anesthesia,but the heart rate and mean arterial pressure at T1 and T2 of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion The application effect of Sevoflurane combined with Remifentanil in laparoscopic myomectomy is good,which can effectively promote postoperative recovery,reduce the incidence of adverse reactions,stabilize hemodynamic indicators,and is worthy of promotion and use.