螺旋CT扫描技术在肺磨玻璃结节良、恶性定性鉴别诊断中的应用

Application of Spiral CT Scanning Technique in the Qualitative Differential Diagnosis of Benign and Malignant Pulmonary Ground Glass Nodules

目的 深入探究螺旋CT扫描技术在鉴别肺磨玻璃结节(GGN)良恶性方面的应用价值,旨在为临床诊疗提供更加精确可靠的依据。方法 选取2020年7月-2023年12月本院收治GGN 101例为研究对象。所有研究对象均行螺旋CT扫描检查,以病理检查为“金标准”,分析螺旋CT扫描技术诊断GGN良、恶性的效果,总结不同性质GGN影像学及形态学特征。结果 经病理确诊:良性GGN36例,恶性GGN65例。101例GGN经螺旋CT扫描技术检查,良性GGN33例,其中AAH26例,炎症10例,恶性GGN64例,其中原位腺癌29例,浸润型腺.癌28例,微浸润腺癌7例。其中良性漏诊3例,符合率91.66%(33/36),恶性漏诊1例.,符合率98.46%(64/65)。螺旋CT扫描技术对GGN良、恶性灵敏度91.66%(33/36),特异度98.46%(64/65),阳性预测值97.05%(33/34),阴性预测值9552%(64/67)。GGN良、恶性组螺旋CT扫描技术影像学及形态学特征比较,差异有统计学意义(P<005)。结论 螺旋CT扫描技术在GGN良、恶性定性鉴别诊断中的应用具有重要意义,为临床医生提供有力的诊断依据,有助于提高GGN的诊断准确性。

Objective The value of spiral CT scanning(MSCT)in identifying the benign and malignant nature of pulmonary ground glass nodules(GGNs)was explored in depth,aiming to provide a more accurate and reliable basis for clinical diagnosis and treatment.Methods 101 cases of GGN admitted to our hospital from July 2020 to December 2023 were selected for the study.All subjects underwent spiral CT scan.Pathological examination was taken as the"gold standard"to analyze the effect of spiral CT scan technology in diagnosing benign and malignant GGN,and to summarize the imaging and morphological characteristics of different GGN properties.Results The diagnosis was confirmed by pathology:36 cases of benign GGN,and 65 cases of malignant GGN.101 GGNs were examined by MSCT,33 benign GGNs,including 26 AAH and 10 inflammatory,and 64 malignant GGNs,including 29 adenocarcinomas in situ,28 invasive adenocarcinomas,and 7 microinvasive adenocarcinomas.There were 3 cases of benign leakage with 91.66%(33/36)compliance and 1 case of malignant leakage with 98.46%(64/65)compliance.MSCT sensitivity for GGN benign and malignant was 91.66%(33/36),specificity was 98.46%(64/65),positive predictive value was 97.05%(33/34),and negative predictive value was 95.52%(64/67).Comparison of MSCT imaging and morphological features between the benign and malignant groups of GGN was statistically significant(P<0.05).Conclusion The application of spiral CT scanning technology in the qualitative differential diagnosis of benign and malignant GGN is of great significance,which provides a strong diagnostic basis for clinicians and helps to improve the diagnostic accuracy of GGN.