摘要
目前重症医学科超级细菌产生逐年增加,给院内感染防控和公共卫生带来许多新挑战。噬菌体是一种能特异性感染并裂解细菌的病毒,为重症多重耐药菌感染的治疗带来新希望。总结了利用噬菌体进行院内环境消杀与监控、治疗重症感染的案例,并分析了在重症医学科中应用噬菌体的问题与可能对策,为噬菌体在重症医学科中的应用研究提供新思路。
At present,the production of superbugs in intensive care medicine is increasing annually,creating new challenges for the treatment of multidrug-resistant bacteria and the prevention and control of hospital-acquired infections.This article summarizes the treatment cases of multidrug-resistant bacteria and the prevention and control of nosocomial infections by bacteriophages,hoping to provide new ideas for the treatment and prevention of multidrug-resistant bacteria.
作者
任德志
李函洋
徐亚奇
童贻刚
段军
REN Dezhi;LI Hanyang;XU Yaqi;TONG Yigang;DUAN Jun(China-Japan Friendship Hospital(Institute of Clinical Medical Sciences),Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100029,China;College of Life Science and Technology,Beijing University of Chemical Technology,Beijing 100029,China;Department of Intensive Care Medicine of China-Japan Friendship Hospital,Beijing 100029,China)
出处
《中国生物工程杂志》
CAS
CSCD
北大核心
2024年第8期148-154,共7页
China Biotechnology
基金
中国高水平医院临床科研业务费(2022-NHLHCRF-LX-03)资助项目。
关键词
噬菌体治疗
重症医学
医院感染
多重耐药菌
Bacteriophage therapy
Critical care medicine
Hospital-acquired infection
Multidrug-resistant bacteria
