糖尿病酮症酸中毒住院患者血糖管理的最佳证据总结

Summary of best evidence for blood glucose management in hospitalized patients with diabetic ketoacidosis

目的检索糖尿病酮症酸中毒(DKA)住院患者血糖管理的相关证据, 总结最佳证据, 给临床和护理提供实践借鉴。方法计算机检索中英文数据库中DKA住院患者血糖管理相关证据, 按照循证检索资源的"6S"证据模型, 采用主题词结合关键词, 依次查找相关的文献。检索时限均为建库至2023年12月31日。对纳入的文献进行质量评价, 筛选符合质量标准的文献, 进行证据提取和汇总。结果共纳入13篇文献, 其中指南7篇、专家共识2篇、临床决策1篇、综述3篇, 从血糖监测、血糖控制、用药管理、护理管理和健康教育4个方面总结出16条最佳证据。结论关于DKA住院患者血糖管理的最佳证据可用于临床实践, 促进DKA住院患者血糖管理的规范化。

Objective To systematically retrieve and summarize the best available evidence on blood glucose management in hospitalized patients with diabetic ketoacidosis(DKA)to provide practical guidance for clinical care.Methods A comprehensive search was conducted in both Chinese and English databases for evidence related to blood glucose management in hospitalized DKA patients.The search followed the"6S"evidence hierarchy model and employed a combination of subject terms and keywords.The search covered all available literature up to December 31,2023.Quality assessment was performed on the identified studies,and those meeting the quality standards were selected for evidence extraction and synthesis.Results A total of 13 documents were included in the review,comprising seven guidelines,two expert consensus statements,one clinical decision-making article,and three reviews.Sixteen best evidence statements were synthesized,focusing on four key areas:blood glucose monitoring,blood glucose control,medication management,nursing management,and health education.Conclusions The best evidence on blood glucose management for hospitalized DKA patients can be effectively applied in clinical practice to standardize the management of blood glucose in this patient population.