BFH-OST和OSTA对绝经后妇女骨质疏松风险预测的对比研究

Comparative study of BFH-OST and OSTA in predicting the risk of osteoporosis in postmenopausal women

目的比较新型北京友谊医院绝经后妇女骨质疏松筛查工具(Beijing Friendship Hospital osteoporosis self-assessment tool,BFH-OST)和亚洲人骨质疏松自我筛查工具(osteoporosis self-assessment tool for Asians,OSTA)对绝经后妇女骨质疏松风险的预测作用。方法随机选取2021年1月至2022年11月就诊于民航总医院的115例绝经后妇女,以双能X射线吸收法(dual energy X-ray absorptiometry,DXA)为诊断标准,通过受试者操作特征曲线(receiver operating characteristic curve,ROC曲线)分析BFH-OST、OSTA的诊断效能。结果BFH-OST和OSTA均与DXA诊断骨质疏松存在明显相关性(P<0.01),BFH-OST的曲线下面积(area under the curve,AUC)为0.819,截断值≤12.2,敏感度为81.25%,特异性为75.90%;OSTA的AUC为0.809,截断值≤–1.2,敏感度为81.25%,特异性72.29%。BFH-OST和OSTA的ROC曲线比较,差异有统计学意义(P<0.05)。结论BFH-OST和OSTA对绝经后妇女骨质疏松风险均有预测作用,BFH-OST的诊断效能优于OSTA。

Objective To compare the predictive effect on the risk of osteoporosis in postmenopausal women with the new Beijing Friendship Hospital osteoporosis self-assessment tool(BFH-OST)and osteoporosis self-assessment tool for Asians(OSTA).Methods A total of 115 postmenopausal women who met the criteria in Civil Aviation General Hospital from January 2021 to November 2022 were randomly enrolled,and dual energy X-ray absorptiometry(DXA)was used as the diagnostic criterion.Analyzing the diagnostic efficacy of BFH-OST and OSTA through receiver operating characteristic(ROC)curve analysis.Results BFH-OST and OSTA were significantly correlated with DXA in the diagnosis of osteoporosis(P<0.01),the area under the curve(AUC)of BFH-OST was 0.819,the cut-off value was≤12.2,the sensitivity was 81.25%,and the specificity was 75.90%.The AUC of OSTA was 0.809,the cut-off value was≤–1.2,the sensitivity was 81.25%,and the specificity was 72.29%.There was a significant difference between the ROC curves of BFH-OST and OSTA(P<0.05).Conclusion BFH-OST and OSTA have predictive effects on the risk of osteoporosis in postmenopausal women.BFH-OST is better than OSTA in predicting and diagnosing osteoporosis in postmenopausal women.