建立具有中国人群代表性的胎儿生长标准的关键要素

Key elements in establishing fetal growth standards representative of the Chinese population

作为产科常用工具,胎儿生长曲线在筛查小于胎龄儿(small for gestational age,SGA)和预测胎儿生长受限(fetal growth restriction,FGR)中发挥着重要作用。然而,目前尚未建立基于中国人群的高质量胎儿生长标准曲线。相对于胎儿生长参考值,制定胎儿生长标准的要求更高。本文围绕建立我国胎儿生长标准的几个关键要素展开叙述,包括研究现场的选择、低风险孕妇的入组、纵向研究的实施、样本量的确定、测量的标准化和质量控制等,旨在确保胎儿生长标准制定的科学性和准确性。

As a commonly used tool in obstetrics,fetal growth curves play an important role in screening for small for gestational age infants and predicting fetal growth restriction.However,a high-quality fetal growth standard curve based on the Chinese population has not yet been established.Compared to fetal growth reference values,fetal growth standards have higher requirements.This article discusses several key elements in establishing fetal growth standards in China,including the selection of research sites,the inclusion of low-risk pregnant women,the implementation of longitudinal study,the determination of sample size,the standardization of measurements,and quality control,aiming to ensure the scientific validity and accuracy of the fetal growth standards.