中医药防治新型冠状病毒感染专家共识

Expert Consensus on TCM Prevention and Treatment of Corona Virus Disease 2019(COVID-19)

目的为进一步明确新型冠状病毒感染的中医病名、病因、核心病机、疾病演变规律、分期论治及通治法,推动中医药行业对新冠病毒感染的统一认识。方法项目严格遵循国际指南的研制规范,经过4轮问卷调查确定临床问题清单,通过文件检索进行GRADE证据分级,并形成推荐意见表单,采用名义组法形成专家共识。结果经过4轮问卷调查确定14项临床问题和12项结局指标。检索10606篇文献,最终纳入145篇并进行GRADE分级,经过29名专家名义群体法形成推荐意见28项,其中强推荐4项,弱推荐24项。结论共识遵循严格的指南制定规范,充分重视一线临床专家意见,体现外感热病及早治疗、通治方和寒温统一理论思想,在最新循证依据的基础上形成具有更高可信性和可操作性的专家共识。

Objective To further clarify the TCM disease name,etiology,core pathogenesis,disease development,treatment of corona virus disease 2019(COVID-19)and promote the unified understanding of COVID-19.Methods This study strictly followed the standard procedure of guidelines development.After 4 rounds of questionnaire survey,the list of clinical issues was determined,the evidence was graded followed the principal of Grading of Recommendations,Assess,Development and Evaluation(GRADE)after document retrieval,and recommendation questionnaires were voted by expert panel.Final expert consensus was formed with nominal group method.Results After 4 rounds of questionnaire survey,14 clinical issues and 12 outcome indicators were identified.After searching 10606 literatures,145 were finally included and graded.A total of 28 recommendations were formed through the nominative group method of 29 experts,including 4 strong and 24 weak recommendations.Conclusion This consensus strictly follows the guidelines,pays full attention to the advices of front-line clinical experts,and reflects the theoretical ideas of early treatment,comprehensive treatment and the unity of cold and heat for exogenous febrile diseases.On the basis of the latest evidence-based evidence,the expert consensus with higher credibility and maneuverability was formed.