症状性颅内动脉狭窄患者HR-MRI特征与卒中风险的关系

Relationship between HR-MRI Features and Stroke Risk in Patient swith Symptomatic Intracranial Artery Stenosis

目的分析症状性颅内动脉狭窄患者高分辨率磁共振成像(HR-MRI)特征与卒中风险的关系。方法选取2021年5月至2022年7月本院收治的87例症状性颅内动脉狭窄患者,图像质量不佳剔除3例患者,最终纳入84例患者。依据缺血性脑卒中诊断标准将38例患者纳入卒中组,剩余46例患者纳入无卒中组。比较两组患者基线资料、HR-MRI特征,进一步Logistic回归分析其与卒中风险的关系。结果两组患者基线资料比较差异无统计学意义(P>0.05);卒中组患者斑块负荷及管腔狭窄率显著高于无卒中组患者(P<0.05),卒中组出现纤维帽与斑块内出血患者显著高于无卒中组患者(P<0.05);Logistic回归分析结果显示斑块负荷、管腔狭窄率、纤维帽及斑块内出血为症状性颅内动脉狭窄患者脑卒中发生的影响因素(P<0.05)。结论斑块负荷、管腔狭窄率、纤维帽及斑块内出血等HR-MRI特征为症状性颅内动脉狭窄患者脑卒中发生的影响因素,临床治疗应密切监测上述指标。

Objective To analyze the relationship between high-resolution magnetic resonance imaging(HR-MRI)features and stroke risk in patients with symptomatic intracranial artery stenosis.Methods 87 patients with symptomatic intracranial artery stenosis admitted to the hospital from May 2021 to July 2022 were selected.Three patients with poor image quality were excluded,and 84 patients were finally included in the study.According to the diagnostic criteria for ischemic stroke,38 patients and 46 patients were included in the stroke group and the non-stroke group,respectively.Baseline data and HR-MRI features of the two groups were comparatively analyzed.The relationship between HR-MRI features and stroke risk was discussed.Results The two groups had comparable baseline data(P>0.05).Compared with the non-stroke group,plaque load and luminal stenosis rate were significantly higher in the stroke group(P<0.05).Patients with fibrous cap and intra-plaque hemorrhage were significantly more in the stroke group(P<0.05).Logistic regression analysis found that plaque load,luminal stenosis rate,fibrous cap and intra-plaque hemorrhage were influencing factors of stroke in patients with symptomatic intracranial artery stenosis(P<0.05).Conclusion HR-MRI features such as plaque load,luminal stenosis rate,fibrous cap,and intra-plaque hemorrhage are influencing factors of stroke in patients with symptomatic intracranial artery stenosis,which deserves close attention in clinical treatment.