服药信念特异性问卷在接受艾滋病抗病毒治疗患者中的适用性评价

Evaluation of the applicability of the beliefs about medical questionnaire-specific in HIV/AIDS patients receiving highly active antiretroviral therapy

目的探讨服药信念特异性问卷(beliefs about medicines questionnaire-specific,BMQ-specific)在接受高效抗逆转录病数治疗(high active autiretrovival therapy,HAAPT)艾滋病患者中的适用性。方法2021年11月至12月,根据云南省艾滋病流行情况,选择3个艾滋病抗病毒治疗点进行调查,采用配额抽样方法选择583例正在接受HAART的艾滋病患者为研究对象。量表的适用性评价包括项目分析、效度检验和信度检验。结果项目分析结果显示,BMQ-specific各条目具有良好的区分度(P<0.001),各项目与对应维度相关系数为0.641~0.820(P<0.001)。内容效度分析结果显示,各条目的内容效度指数>0.78,量表的内容效度指数为0.970。探索性因素分析和验证性因素分析结果显示模型拟合指标均在标准范围内。BMQ-specific两个维度与Morisky依从性评估量表得分均存在相关(P<0.01)。信度分析结果显示必要性和顾虑性维度Cronbach’sα分别为0.854和0.790,特定项目与总体相关系数值均>0.5,特定项目删除后的克隆巴克系数均小于对应维度的Cronbach’sα值。4周后服药必要性和顾虑性重测信度分别为0.786和0.753。结论BMQ-specific中文版在接受HAART患者中被证实有较好的适用性。

Objective To investigate the applicability of beliefs about medicines questionnaire specific(BMQ-specific)in HIV/AIDS patients receiving highly active antiretroviral therapy(HAART).Methods From November to December in 2021,583 HIV/AIDS patients receiving HAART in 3 clinical treatment sites were selected according to the prevalence of HIV/AIDS in Yunnan Province by matched sampling.The applicability evaluation of the scale includes item analysis,validity and reliability test.Results BMQ-specific had good discrimination(P<0.001),and the correlations between score of each item and the respective dimension total score ranged from 0.641-0.820(P<0.001).The results of exploratory factor analysis and validation confirmatory factor analysis showed that the model fitting indicators were within the standard range.The item-content validity index of each item was beyond 0.78,and the scale-content validity index was 0.970.BMQ-specific scores were significantly correlated with the Morisky medication adherence scale 8-item version(P<0.001).Reliability analysis showed that the Cronbach’sαof necessity and concern were 0.854 and 0.790 respectively,and the corrected item-total correlation values of 10 items were larger than 0.5,if item deleted was all smaller than the Cronbach’sαin the corresponding dimensions,the test-retest reliability of the two dimensions with for-week interval was 0.786 and 0.753.Conclusion The Chinese version of BMQ-specific had proved its good applicability in HIV/AIDS patients receiving HAART.