磁共振T2 mapping技术在心肌梗死后对存活心肌评价的应用研究

Application of magnetic resonance T2 mapping technique in the evaluation of surviving myocardium after myocardial infarction

目的探讨磁共振T2mapping成像技术在判断心肌梗死(MI)患者中存活心肌的临床应用价值。方法回顾性分析22例MI急性期患者、23例MI慢性期患者及31例健康志愿者(对照组)的磁共振影像资料,应用CVI42软件测量各组患者心肌节段的T2值并进行统计学分析。结果对照组心肌、MI急性期远隔梗死区心肌、MI慢性期远隔梗死区心肌的T2值分别为(48.14±5.59)ms、(50.29±2.13)ms、(49.00±3.25)ms,3组比较差异无统计学意义(P>0.05);MI急性期梗死心肌区、MI慢性期梗死心肌区的T2值分别为(59.99±5.44)ms、(60.24±6.60)ms,急性期、慢性期梗死心肌区T2值和正常心肌(包括远隔梗死区心肌)T2值比较差异有统计学意义(P<0.05)。结论急性期、慢性期的MI患者在梗死心肌周围都存在缺血心肌,应用T2 mapping技术可以显示梗死核心区、可挽救心肌区、正常心肌的分布范围。

Objective To evaluate the clinical value of magnetic resonance T2 mapping in diagnosing myocardial survival in patients with myocardial infarction(MI).Methods Magnetic resonance imaging data of 22 patients with acute MI stage,23 patients with chronic MI stage and 31 healthy volunteers(control group)were retrospectively analyzed.CVI42 software was used to measure the cardiac muscle segment T2 value of each group and perform statistical analysis.Results The T2 values of control myocardium,the myocardium in the acute stage of MI and the myocardium in the remote infarction area of MI chronic stage were(48.14±5.59)ms,(50.29±2.13)ms and(49.00±3.25)ms,respectively,and there was no significant difference among the three groups(P>0.05).The T2 values of myocardial infarction in acute stage and chronic stage of MI were(59.99±5.44)ms and(60.24±6.60)ms,respectively,and the T2 values of myocardial infarction in acute stage and chronic stage were significantly different from those of normal myocardes(including those in distant infarction areas)(P<0.05)..Conclusion There is ischemic myocartis around the infarcted myocartis in both acute and chronic MI patients.T2 mapping can be used to show the distribution range of the infarcted core area,salvageable myocartis and normal myocartis.