干旱地区官兵健康体检中血尿酸水平与其影响因素的相关性分析

Correlation Analysis of Serum Uric Acid Levels and Influencing Factors in Health Examinations of Military Personnel in Arid Regions

目的:调查干旱地区官兵2022年度健康体检中HUA(高尿酸血症)的患病情况,分析其相关影响因素,了解流行病学数据,为更好防治HUA提供理论依据。方法:纳入2022年1月至10月在某部队医院参加健康体检的1 863名男性官兵,比较不同年龄段HUA患病率及血尿酸水平;对HUA者和随机抽取的416名尿酸正常者的生化指标、血糖代谢异常率、血脂异常率和高血压患病率进行分析,并采用多因素Logistic回归方法分析影响HUA发病的相关因素。结果:HUA总体患病率为25.50%;HUA组收缩压、舒张压、空腹血糖、TG、TC、BMI均高于尿酸正常组(P<0.05),其血糖代谢异常率、血脂异常率和高血压患病率均高于尿酸正常组(P<0.05);血尿酸水平和TG、收缩压、舒张压、BMI呈弱的正相关,与HDL-C呈负相关,与空腹血糖和LDL-C无相关性;多因素Logistic回归分析显示,肥胖、高血压、血脂代谢异常是HUA发生的独立危险因素。结论:干旱地区男性官兵HUA患病率较高,应通过健康宣教、合理膳食、适宜运动和跟踪随访等措施尽早防治HUA。

Objective:To investigate the prevalence of hyperuricemia(HUA)during the 2022 physical examination for officers and soldiers in arid a rea,analyze its related influencing factors,understand epidemiological data,and provide theoretical basis for better prevention and treatment of HUA.Methods:A total of 1863 male officers and soldiers who participated in physical examinations in a military hospital from January to October 2022 were included.The prevalence of HUA and serum uric acid levels in different age groups were compared;416 patients with HUA and those with normal blood uric acid were randomly selected to analyze the biochemical indicators,the rates of abnormal blood glucose metabolism,abnormal blood lipid,and hypertension prevalence in two groups,and the influencing factors of HUA were analyzed using multivariate logistic analysis.Results:The overall prevalence rate of HUA was 25.50%.The systolic blood pressure,diastolic blood pressure,fasting blood glucose,TG,TC,and BMI in the HUA group were higher than those in the normal uric acid group(P<0.01).The rate of abnormal blood glucose metabolism,abnormal blood lipids,and the prevalence rate of hypertension in the HUA group were higher than those in the normal uric acid group(P<0.01).Serum uric acid levels were weakly positively correlated with TG,systolic blood pressure,diastolic blood pressure and BMI,negatively correlated with HDL?C,but there is no correlation between fasting blood glucose and LDL-C.Multivariate logistic regression analysis showed that obesity,hypertension,and abnormal lipid metabolism were independent risk factors for HUA.Conclusion:The prevalence of HUA in male officers and soldiers in arid area is high,and measures such as health education,reasonable diet,appropriate exercise,and follow-up should be taken to prevent and treat HUA as early as possible.