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成人感染新冠病毒后致非典型溶血尿毒综合征1例

A Case of Atypical Hemolytic Uremic Syndrome in Adults Infected with SARS-CoV-2
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摘要 非典型溶血尿毒综合征(atypical Hemolytic Uremic Syndrome,a HUS)是一种较为罕见的疾病,成人发病率全球每年约0.2/10万,在早期诊断及干预方面都较为复杂,有着较高的病死率,患者中半数以上可能会进展至终末期肾病(End Stage Renal Disease,ESRD)。本文报道了1例新冠病毒感染后致aHUS的成年病例,经我院收治后诊疗尚佳,现结合相关文献,对本例患者的诊疗过程、aHUS的诊断、机制及治疗方案进行如下概述。 Atypical hemolytic uremic syndrome(aHUS)is a relatively rare disease with an adult incidence of about 2 per million per year worldwide,which is complex in early diagnosis and intervention,resulting in a high mortality rate,and more than half of patients may progress to end-stage renal disease(ESRD).In this paper,we report an adult case of aHUS caused by SARS-CoV-2 infection,and the diagnosis and treatment of aHUS are summarized as follows based on relevant literature.
作者 董香迎 钟晨 陈雪茹 房文栋 闫畅 张丽翠 DONG Xiang-ying;ZHONG Chen;CHEN Xue-ru;FANG Wen-dong;YAN Chang;ZHANG Li-cui(Shihezi University School of Medicine,Xinjiang Shihezi,832002;Department of Thyroid and Breast Surgery,the First Affiliated Hospital of Shihezi University,Xinjiang Shihezi,832008;Examination Cenre,the First Affiliated Hospital of Shihezi University,Xinjiang Shihezi,832008)
出处 《农垦医学》 2024年第3期285-288,共4页 Journal of Nongken Medicine
基金 2023年度兵团指导性科技计划项目(2023ZD011) 2022年度自主资助支持校级科研项目(ZZZC2022075)。
关键词 新冠病毒 非典型溶血尿毒综合征 血栓性微血管病 补体替代途径 SARS-CoV-2 Hemolytic uremic syndrome Thrombotic microangiopathy Complement alternative pathway
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