儿童阻塞性睡眠呼吸暂停对颌面发育的影响和机制

Effect and mechanism of obstructive sleep apnea on maxillofacial development in children

近年来,大量的研究证实儿童阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)会使儿童颌面部发育异常,而颌面部的异常发育可能导致OSA病情持续发展以及颌面部的持续异常发育,对孩子身心造成不利影响。了解OSA对儿童颌面发育的影响和机制,有助于更好地预防及治疗儿童OSA以及颌面发育不良问题。

In recent years,a large number of studies have demonstrated that obstructive sleep apnea(OSA)can lead to the abnormal development of maxillofacial region in pediatric patients,which may result in a'vicious circle'aggravating OSA,therefore adversely affecting quality of life.Understanding the effect and mechanism of OSA on children's maxillofacial development is helpful to better prevent and treat OSA and maxillofacial dysplasia in children.