胶原凝胶联合血肿方外敷在腹部切口愈合不良中应用效果

Effectiveness of Collagen Gel Combined with Haematoma Formula Topical Application in Poorly Healing Abdominal Incisions

目的:探究胶原凝胶联合血肿方外敷在腹部切口愈合不良中应用效果。方法:选取2020年1月—2023年10月银川市第二人民医院等4家医院治疗的80例腹部切口愈合不良患者作为研究对象,应用随机数表法将其分为对照组(传统换药)及研究组(胶原凝胶联合血肿方外敷),每组各40例。比较两组愈合情况、临床指标(切口红肿消退时间、表面切口愈合时间、住院时间)、切口疼痛评分[疼痛视觉模拟量表(VAS)]、炎症因子[肿瘤坏死因子(TNF-α)、C反应蛋白(CRP)]及切口愈合满意度。结果:研究组甲级愈合率高于对照组,差异有统计学意义(P<0.05);研究组切口红肿消退时间、表面切口愈合时间、住院时间短于对照组,差异有统计学意义(P<0.05);治疗后,两组VAS评分、TNF-α、CRP水平均降低,研究组低于对照组,差异有统计学意义(P<0.05);研究组切口愈合满意度高于对照组,差异有统计学意义(P<0.05)。结论:腹部切开不良患者接受胶原凝胶联合血肿方外敷可减轻炎症反应,缩短愈合时间,促进愈合,满意度较高。

Objective:To investigate the application effect of collagen gel combined with haematoma formula externally applied in abdominal incision poor healing.Method:A total of 80 patients with poor abdominal incision healing were selected from four hospitals including Yinchuan Second People's Hospital from January 2020 to October 2023 as the study objects,and divided into control group(traditional dressing change)and study group(collagen gel combined with hematoma prescription external application)by random number table method,with 40 cases in each group.The healing status,clinical indexes(time to resolution of incision redness,healing time of surface incision,length of hospital stay),incision pain score[visual analogue scale of pain(VAS)],inflammatory factors[tumor necrosis factor(TNF-α),C-reactive protein(CRP)],and incision healing satisfaction were compared between the two groups.Result:The Grade A healing rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).The time of incision redness resolution,surface incision healing time and hospital stay in the study group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After treatment,VAS score,TNF-αand CRP levels of both groups were decreased,and the study group was lower than the control group,the difference was statistically significant(P<0.05).The wound healing satisfaction of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:In patients with poor abdominal incision,collagen gel combined with hematoma prescription can reduce inflammation,shorten healing time,promote healing,and have a high satisfaction.