白带常规及细菌性阴道病3项检测对女性阴道微生态的评估价值分析

Analysis of the value of leucorrhea routine and 3 tests for bacterial vaginosis in assessing vaginal microecology in women

目的 分析白带常规及细菌性阴道病(BV)3项检测对女性阴道微生态的评估价值。方法 110例常规体检女性,采集阴道分泌物,进行pH值测定、阴道清洁度评估以及唾液酸苷酶、过氧化氢和白细胞酶的细菌性阴道病3项检测。分析110例受检者的阴道微生态情况;比较不同阴道微生态受检者的白带常规及细菌性阴道病3项检测结果。结果 110例受检者中,正常菌群状态41例、菌群失调29例,菌群增殖过度10例,菌群抑制30例,占比分别为37.27%、26.36、9.09%、27.27%。菌群失调、菌群抑制受检者阴道pH值≤4.6占比分别为13.79%、6.67%,明显低于阴道微生态正常受检者的97.56%(P<0.05)。菌群失调、菌群增殖过度、菌群抑制受检者阴道清洁度Ⅰ~Ⅱ度占比分别为10.34%、40.00%、36.67%,明显低于阴道微生态正常受检者的95.12%(P<0.05)。阴道微生态正常受检者中唾液酸苷酶、过氧化氢和白细胞酶大多数呈阴性。菌群失调、菌群抑制受检者过氧化氢阳性率明显高于阴道微生态正常受检者(P<0.05);菌群失调、菌群增殖过度、菌群抑制受检者白细胞酶阳性率明显高于阴道微生态正常受检者(P<0.05);菌群失调受检者唾液酸苷酶阳性率高于阴道微生态正常受检者(P<0.05)。结论 白带常规及细菌性阴道病3项检测是评估女性阴道微生态的有效方法 ,对于阴道健康的维护具有重要临床价值。

Objective To analyze the value of leucorrhea routine and 3 tests for bacterial vaginosis(BV)in assessing vaginal microecology in women.Methods In 110 women undergoing routine physical examination,vaginal secretions were collected for pH measurement,assessment of vaginal cleanliness,and 3 tests of sialidase,hydrogen peroxide and leucocyte esterase for bacterial vaginosis.The vaginal microecology of the 110 subjects was analyzed;the results of routine leukorrhea and the 3 tests for bacterial vaginosis were compared among subjects with different vaginal microecology.Results Among the 110 subjects,there were 41 cases of normal flora status,29 cases of dysbiosis,10 cases of hyperproliferation of flora,and 30 cases of inhibition of flora,accounted for 37.27%,26.36,9.09%,and 27.27%,respectively.The percentages of vaginal pH≤4.6 in the subjects with dysbiosis and inhibition of flora were 13.79%and 6.67%,which were significantly lower than 97.56%of the subjects with normal vaginal microecology(P<0.05).The percentage of vaginal cleanliness of gradeⅠ-Ⅱin the subjects with dysbiosis,overproliferation and inhibition of flora were 10.34%,40.00%and 36.67%,which was significantly lower than 95.12%in the subjects with normal vaginal microecology(P<0.05).Sialidase,hydrogen peroxide and leucocyte esterase were mostly negative in normal vaginal microecology subjects.The positive rates of hydrogen peroxide in patients with dysbiosis and inhibition of flora were significantly higher than those in patients with normal vaginal microecology(P<0.05).The positive rate of leukocyte esterase in the patients with dysbiosis,overproliferation and inhibition of flora was significantly higher than that in the patients with normal vaginal microecology(P<0.05).The positive rate of sialidase in subjects with dysbiosis was higher than that in subjects with normal vaginal microecology(P<0.05).Conclusion Leucorrhea routine and 3 tests for bacterial vaginosis are effective methods for assessing the vaginal microecology of a woman and are of great clinical value in the maintenance of vaginal health.