穴位敷贴疗法联合干扰素α1b雾化对儿童支气管炎患者的疗效及气道炎症反应的影响

Effect of Acupoint Application Therapy Combined with Interferonα1b Nebulization for Children with Bronchitis and Airway Inflammatory Response

目的探究穴位敷贴疗法联合干扰素α1b雾化对儿童支气管炎患儿的疗效及气道炎症反应的影响。方法将2022年5月—2023年5月在本院进行治疗的支气管炎患儿100例作为研究对象,采用盲法将其均分为实验组(n=50)和参比组(n=50)。其中,参比组采用常规治疗,实验组采用穴位敷贴疗法联合干扰素α1b雾化,对比两组治疗效果、不良反应及治疗前后气道炎症反应。结果实验组的总有效率明显高于参比组(P=0.037);治疗后,两组CRP水平均降低,且实验组CRP低于参比组(P<0.05);实验组的不良反应率明显低于参比组(P=0.025)。结论穴位敷贴疗法联合干扰素α1b雾化可有效提高对支气管炎患儿的治疗效果,减轻气道炎症反应与不良反应,值得临床借鉴应用。

Objective To explore acupoint application therapy combined with interferonαof 1b nebulization on airway inflammatory response of children with bronchitis.Methods The paper chose 100 children with bronchitis in our hospital from May 2022 to May 2023 as study subjects,and divided them into experimental group(n=50)and control group(n=50)with blind method.Reference group was treated with routine treatment,while experimental group with acupoint application therapy combined with interferonα1b nebulization.Curative effect,adverse rea ctions,and airway inflammation reactions were compared before and after treatment between two groups.Results Total effective rate of 94.00%in experimental group was significantly higher than 80.00%in reference group(P=0.037).After treatment,CRP levels in both groups decreased,CRP levels in experimental group were lower than control group(both P<0.05).Adverse reaction rate in experimental group was 4.00%,significantly lower than 18.00%in reference group(P=0.025).Conclusion Acupoint application therapy combined with interferonα1b nebulization can improve curative effect on children with bronchitis,reduce airway inflammation and adverse reactions effectively,which is worthy of clinical reference and application.