不同剂量雌激素对宫腔镜粘连分离术后患者的疗效分析

Curaitve Effect Analysis of Different Doses of Estrogen for Patients After Hysteroscopic Adhesiolysis Surgery

目的研究不同剂量雌激素对宫腔镜粘连分离术后患者的治疗效果。方法选择2021年8月—2023年8月在本院接受治疗的88例宫腔粘连患者为研究对象,所有患者均实施宫腔镜粘连分离术治疗。按随机数字法将患者分为观察组与对照组,每组44例。两组患者术后均采用雌二醇/地屈孕酮片(芬吗通)治疗,观察组每日用量为2mg,对照组每日用量为4mg。对比两组患者粘连类型评分与累及范围评分,以及不良反应发生率。结果治疗后,观察组粘连类型评分与累及范围评分与对照组患者比较,差异无统计学意义(P>0.05);观察组不良反应发生率低于对照组(P<0.05)。结论实施低剂量雌激素治疗能够显著降低宫腔镜粘连分离术后患者的不良反应发生率。该方法疗效可靠,安全性高,因此,值得临床广泛应用。

Objective To study curative effect of different doses of estrogen on patients after hysteroscopic adhesiolysis surgery.Methods The paper chose 88 patients with intrauterine adhesions with hysteroscopic adhesiolysis treatment in our hospital from August 2021 to August 2023 as analysis subjects,and divided them into observation group and control group randomly,with 44 cases in each group.Both groups were treated with estradiol/dexmedetone tablets(Fenmutong).Observation group was treated with daily dose of 2 milligrams,while control group with daily dose of 4 milligrams.Adhesive type scores and involvement range scores were compared between two groups,incidence of adverse reactions was compared between two groups.Results After treatment,there was no significant difference in adhesion type scores and affected range scores between observation group and control group.Incidence of adverse reactions in observation group was lower than control group(P<0.05).Conclusion Low-dose estrogen therapy can help reduce adverse reactions,which is worthy of clinical application.