超声剪切波弹性成像参数应用于病毒性肝炎患者肝硬化程度评估中的临床价值探析

Clinical value of ultrasound shear wave elastography parameters in evaluating the degree of liver cirrhosis in patients with viral hepatitis

目的:探析超声剪切波弹性成像参数应用于病毒性肝炎患者肝硬化程度评估中的临床价值。方法:选取2022年3月—2023年2月淄博市传染病医院收治的135例病毒性肝炎患者,应用超声剪切波弹性成像技术进行诊断并收集参数,根据Child-Pugh分级将肝硬化患者分为A-B级92例,C级43例,比较两组的超声剪切波弹性成像参数,分析其应用于病毒性肝炎患者肝硬化程度评估中的临床价值。结果:Child-Pugh分级C级的病毒性肝炎患者弹性模量、剪切波速度高于Child-Pugh分级A-B级(P<0.05);超声剪切波弹性成像参数弹性模量、剪切波速度与病毒性肝炎肝硬化程度有关(P<0.05);超声剪切波弹性成像参数弹性模量、剪切波速度应用于病毒性肝炎患者肝硬化程度评估中的受试者工作特征曲线下面积分别为0.870、0.865,均有一定的诊断价值。结论:超声剪切波弹性成像参数在病毒性肝炎患者肝硬化程度评估中具有较高的临床诊断价值,尤其是弹性模量和剪切波速度这两个参数在评估肝硬化程度方面表现出良好的相关性和诊断准确率,为临床提供了一种可靠的诊断工具和参考依据。

Objective To explore the clinical value of ultrasound shear wave elastography parameters in evaluating the degree of cirrhosis in patients with viral hepatitis.Methods A total of 135 patients with viral hepatitis who were treated in Zibo City Infectious Disease Hospital from March 2022 to February 2023 were selected.Ultrasound shear wave elastography technology was used for diagnosis and the parameters were collected.According to the Child Pugh classification,liver cirrhosis patients were divided into A-B grade 92 cases and C grade 43 cases.The ultrasound shear wave elastography parameters of the two groups were compared,and their clinical value in evaluating the degree of liver cirrhosis in viral hepatitis patients was analyzed.Results The elastic modulus and shear wave velocity of hepatitis patients with Child-Pugh grade C were higher than those with Child-Pugh grade A-B(P<0.05).The elastic modulus and shear velocity of ultrasonic shear wave elastic imaging parameters were correlated with the degree of liver cirrhosis of viral hepatitis(P<0.05).The area under the receiver operating characteristic curve of ultrasonic shear wave elastic modulus and shear wave velocity in evaluating the degree of cirrhosis in patients with viral hepatitis were 0.870 and 0.865,respectively,which had certain diagnostic value.Conclusion The parameters of ultrasound shear wave elastography have high clinical diagnostic value in evaluating the degree of liver cirrhosis in patients with viral hepatitis,especially the elastic modulus and shear wave velocity,which show good correlation and diagnostic accuracy in evaluating the degree of liver cirrhosis,providing a reliable diagnostic tool and reference basis for clinical practice.