基于中医传承辅助平台分析岐黄学者亢泽峰治疗高度近视用药规律

Analysis of Medication for Treating High Myopia by Qihuang Scholar KANG Zefeng Based on the TCM Inheritance Assistance Platform

目的 基于中医传承辅助平台对岐黄学者亢泽峰治疗高度近视的医案进行数据挖掘及分析,总结其治疗高度近视的用药规律及学术思想。方法 收集2020年1月—2023年6月中国中医科学院眼科医院亢泽峰门诊治疗高度近视的处方,通过中医传承辅助平台临床信息采集系统建立医案数据库,对所有中药名称规范化处理后进行频数统计、关联规则分析、聚类分析等数据挖掘及统计。结果 共纳入方剂52首,共涉及药物98味。药性以寒、温居多;药物归经以肝经、肾经、心经三经为主;药味以苦味、辛味、甘味居多。药物频数居前7位的是枸杞子、当归、茺蔚子、菟丝子、三七、石菖蒲、远志,其中以枸杞子为核心药物,与菟丝子、茺蔚子、石菖蒲、远志等药物关联密切。结论 亢泽峰治疗高度近视基于“瞳神络病”理论,以补肝肾、调气血为主,通目络为要,疗效甚佳,体现了高度近视中运用络病理论指导下的诊治思路及用药特色。

OBJECTIVE To perform data mining and analysis on the medical cases of Qihuang Scholar KANG Zefeng's treatment of high myopia using Traditional Chinese Medicine(TCM)Inheritance Assistance Platform,summarizing his medication patterns and academic thoughts for treating high myopia.METHODS Prescriptions for high myopia treated by KANG Zefeng at the Eye Hospital,China Academy of Chinese Medical Sciences from January 2020 to June 2023 were collected.A medical case database was established through the Clinical Information Collection System of TCM Inheritance Assistance Platform.Standardize the names of all Chinese medicines,and then data mining and statistics,such as frequency statistics,association rule analysis,and cluster analysis,were conducted.RESULTS A total of 52 prescriptions were included,involving 98 types of medications.The properties of the medications were mostly cold and warm;The meridian tropism primarily involved the liver,kidney,and heart meridians;The flavors of the medications were predominantly bitter,pungent,and sweet.The top seven frequently used medications were goji berries,Angelica,Motherwort,Dodder seed,Notoginseng,Acorus,and Polygala,with Goji berries being the core medication,closely associated with Dodder seed,Motherwort,Acorus,and Polygala.CONCLUSIONS KANG Zefeng's treatment of high myopia is based on the theory of"pupil collateral disease",focusing on nourishing liver and kidney,regulating Qi and blood,and emphasizing the importance of unblocking the collaterals in the eyes.The treatment has proven to be highly effective,showcasing the diagnostic and medication characteristics guided by the collateral disease theory in treating high myopia.