真武汤治疗心力衰竭研究文献可视化分析

Visualization Analysis on Research Literature about Zhenwu Decoction in Treating Heart Failure

目的基于文献计量学方法系统梳理真武汤治疗心力衰竭研究文献,了解该领域研究现状、研究热点并预测未来发展趋势。方法检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)、中国生物医学文献服务系统(SinoMed)建库至2023年7月20日收录的真武汤治疗心力衰竭研究文献,利用CiteSpace6.1.R6软件构建作者、机构合作网络知识图谱,构建关键词共现、聚类、时间线和突现知识图谱。结果共纳入文献826篇,年发文量呈波动上升趋势,发文量最高的作者为李文杰,并形成以李文杰、程晓昱、赵凤林为代表的研究团队;发文量最高的研究机构为辽宁中医药大学附属医院。出现频次最高的关键词为“慢性心力衰竭”,关键词共聚为12类,突现强度较高的关键词为“心功能”“血府逐瘀汤”“冠心病”。结论真武汤治疗心力衰竭的研究随着临床应用范围的逐渐扩大,关注度逐渐升高,但各作者、机构间的合作交流较少,目前心功能、血府逐瘀汤、网络药理学、作用机制、冠心病、葶苈大枣泻肺汤是当前的研究热点,今后该领域热点可能是真武汤联合其他方剂治疗不同类型心衰的临床疗效、作用机制。

Objective To systematically review the research literature about the treatment of heart failure with Zhenwu Decoction based on CiteSpace;To understand the current research status and hotspots in this field;To predict future development trends.Methods Research literature about the treatment of heart failure with Zhenwu Decoction was retrieved from CNKI,Wanfang Data,VIP,and Sino Med from the establishment of the databases to July 20,2023.CiteSpace 6.1.R6 software was used to construct a knowledge graph of author and institutional collaboration networks,and construct a knowledge graph of keyword co-occurrence,clustering,timeline,and emergence.Results A total of 826 articles were included,and the annual publication volume showed a fluctuating upward trend.The author with the highest publication volume was Li Wenjie,and a research teams represented by Li Wenjie,Cheng Xiaoyu,and Zhao Fenglin were formed;the research institution with the highest number of publications was the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine.The most frequently occurring keyword was“chronic heart failure”.The keywords were clustered into 12 categories,with the most prominent keywords being“heart function”,“Xuefu Zhuyu Decoction”,and“coronary heart disease”.Conclusion Research on the treatment of heart failure with Zhenwu Decoction has seen a gradual rise in attention with the gradual expansion of clinical applications,but there has been less collaborative communication between authors and institutions.At present,cardiac function,Xuefu Zhuyu Decoction,network pharmacology,mechanism,coronary heart disease,and Tingli Dazao Xiefei Decoction are the hotspots of current research,and the hotspots of this field in the future may be the clinical efficacy and the mechanism of the Zhenwu Decoction combining with other formulas in the treatment of different types of heart failure.