乙型肝炎病毒相关肝细胞癌风险预测模型

Risk prediction model of hepatitis B associated hepatocellular carcinoma

肝癌是全球常见的恶性肿瘤之一,严重威胁人类身体健康,乙型肝炎病毒感染是肝癌最常见病因之一。大多数肝癌诊断时已进展至中晚期,预后差,早发现、早诊断、早治疗是改善其临床转归的重要支撑。近年来,国内外学者建立了各种肝癌风险预测模型,有利于提高肝癌早期诊断率和降低病死率。该文就慢性乙型肝炎相关肝癌的危险因素及风险预测模型进行综述,以期为HBV相关肝癌风险监测和管理决策提供参考。

Hepatocellular carcinoma is one of the most common malignant tumors in the world,which is a serious threat to human health.HBV infection is one of the most common causes of hepatocellular carcinoma.The diagnosis of most hepatocellular carcinoma has progressed to the middle and late stage,and the prognosis is poor.Early detection,diagnosis and treatment are important supports to improve the clinical outcome of hepatocellular carcinoma.In recent years,scholars at home and abroad have established various hepatocellular carcinoma risk prediction models,which are conducive to improving the early diagnosis rate of hepatocellular carcinoma and reducing the mortality rate.This article reviews the risk factors and risk prediction models of chronic hepatitis B associated hepatocellular carcinoma,in order to provide reference for HBV-associated liver cancer risk monitoring and management decision.