PET/MRI在头颈部肿瘤中的应用价值

Application value of PET/MRI in head and neck cancer

头颈部肿瘤是常见的恶性肿瘤之一,多数患者确诊时已处于疾病中晚期,因此头颈部肿瘤的早期诊断、准确分期及疗效监测是优化治疗策略及改善预后的关键。一体化正电子发射断层扫描/磁共振成像(positron emission tomography/magnetic resonance imaging,PET/MRI)整合了分子功能与解剖结构成像,实现了PET与MRI的优势互补,将PET代谢功能信息与MRI良好软组织对比度相结合,真正实现多模态成像,在肿瘤诊疗过程中具有重要临床意义。文章主要探讨PET/MRI在头颈部肿瘤诊断分期、监测疗效、预测预后及制定放疗计划等方面的应用及进展。

Head and neck cancer is one of the common malignant tumors,and most patients are diagnosed in the middle or late stages of the disease.Therefore,early diagnosis,accurate staging,and efficacy monitoring are the key to optimizing treatment strategies and improving prognosis of head and neck cancer.Integrated positron emission tomography/magnetic resonance imaging(PET/MRI)combines molecular function and anatomical structure imaging,harnessing the complementary advantages of PET and MRI.By combining the metabolic information of PET with the excellent soft tissue contrast of MRI,it truly achieves multimodal imaging,which is of significant clinical importance in the diagnosis,treatment,and monitoring of tumors.This review mainly focuses on the application and progress of PET/MRI in the diagnosis,staging,monitoring of efficacy,prognosis prediction,and development of radiotherapy plans for head and neck cancer.